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Aesthetic Plast Surg. 1980 Dec;4(1):343-8. doi: 10.1007/BF01575237.

The role of diazepam in skin hyperpigmentation.

Aesthetic plastic surgery

J A Ferreira

Affiliations

  1. Department of Surgery, Mission Community Hospital, 27852 Puerta Real Highway, Suite 112, 92691, Mission Viejo, California, USA.

PMID: 24174099 DOI: 10.1007/BF01575237

Abstract

Dermabrasion of the face for multiple conditions requiring reconstructive surgery continues to be a valuable procedure. An important complication of the procedure, however, in the form of hyperpigmentation, led to a search for the cause. When normal anatomic studies failed to indicate a valid reason for this complication in a female patient, further search revealed a biochemical reason-diazepam (Valium). Treatment with a bleaching agent, hydroquinone ointment, reversed the hyperpigmentation and led to a permanent satisfactory result.

References

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  2. Aesthetic Plast Surg. 1976 Dec;1(1):381-9 - PubMed
  3. J Invest Dermatol. 1974 Apr;62(4):436-49 - PubMed
  4. J Pharm Sci. 1973 Nov;62(11):1789-96 - PubMed

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