Display options
Cite
Belyaev DK, Ruvinsky AO, Agulnik AI, et al. Effect of hydrocortisone on the phenotypic expression and inheritance of the Fused gene in mice. Theor Appl Genet. 1983;64(4):275-81doi: 10.1007/BF00274161.
Belyaev, D. K., Ruvinsky, A. O., Agulnik, A. I., & Agulnik, S. I. (1983). Effect of hydrocortisone on the phenotypic expression and inheritance of the Fused gene in mice. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 64(4), 275-81. https://doi.org/10.1007/BF00274161
Belyaev, D K, et al. "Effect of hydrocortisone on the phenotypic expression and inheritance of the Fused gene in mice." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 64,4 (1983): 275-81. doi: https://doi.org/10.1007/BF00274161
Belyaev DK, Ruvinsky AO, Agulnik AI, Agulnik SI. Effect of hydrocortisone on the phenotypic expression and inheritance of the Fused gene in mice. Theor Appl Genet. 1983 Mar;64(4):275-81. doi: 10.1007/BF00274161. PMID: 24265074.
Copy Download .nbib Format: NLM
Share it on

Theor Appl Genet. 1983 Mar;64(4):275-81. doi: 10.1007/BF00274161.

Effect of hydrocortisone on the phenotypic expression and inheritance of the Fused gene in mice.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

D K Belyaev, A O Ruvinsky, A I Agulnik, S I Agulnik

Affiliations

  1. Siberian Department Academy of Sciences of the USSR, Institute of Cytology and Genetics, Novosibirsk, USSR.

PMID: 24265074 DOI: 10.1007/BF00274161

Abstract

This study was undertaken to examine the effects of hydrocortisone injected into male mice on the phenotypic expression and inheritance of the Fused (Fu) gene in their offspring. Data were obtained indicating that there is a hydrocortisone-susceptible period during spermatogenesis. Hydrocortisone injections of males during this period resulted in a statistically significant decrease in the proportion of phenotypically Fu offspring. Genetic analysis with the use of the closely linked recessive marker tufted (tf) demonstrated that the deficit of phenotypically Fu individuals among offspring is not caused by the differential death of gametes, zygotes or embryos. According to genetic data, this deficit is due to a decrease in the penetrance of the Fu gene and partly to its inherited inactivation. The possible mechanisms of the observed phenomenon are discussed.

References

  1. Probl Endokrinol (Mosk). 1968 Mar-Apr;14(2):75-7 - PubMed
  2. Genetics. 1962 Mar;47:285-303 - PubMed
  3. J Hered. 1981 Jul-Aug;72(4):267-74 - PubMed
  4. Genetics. 1937 Jan;22(1):1-13 - PubMed
  5. Genet Res. 1967 Apr;9(2):211-20 - PubMed
  6. J Hered. 1979 Sep-Oct;70(5):301-8 - PubMed
  7. Nature. 1979 May 3;279(5708):38-42 - PubMed
  8. Proc Natl Acad Sci U S A. 1981 May;78(5):3147-50 - PubMed
  9. Int Rev Cytol. 1979;58:1-114 - PubMed
  10. Differentiation. 1977;7(3):167-80 - PubMed
  11. J Hered. 1981 Mar-Apr;72(2):107-12 - PubMed

Publication Types