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Jensen FB. Influence of nucleoside triphosphates, inorganic salts, NADH, catecholamines, and oxygen saturation on nitrite-induced oxidation of rainbow trout haemoglobin. Fish Physiol Biochem. 1993;12(2):111-7doi: 10.1007/BF00004376.
Jensen, F. B. (1993). Influence of nucleoside triphosphates, inorganic salts, NADH, catecholamines, and oxygen saturation on nitrite-induced oxidation of rainbow trout haemoglobin. Fish physiology and biochemistry, 12(2), 111-7. https://doi.org/10.1007/BF00004376
Jensen, F B. "Influence of nucleoside triphosphates, inorganic salts, NADH, catecholamines, and oxygen saturation on nitrite-induced oxidation of rainbow trout haemoglobin." Fish physiology and biochemistry vol. 12,2 (1993): 111-7. doi: https://doi.org/10.1007/BF00004376
Jensen FB. Influence of nucleoside triphosphates, inorganic salts, NADH, catecholamines, and oxygen saturation on nitrite-induced oxidation of rainbow trout haemoglobin. Fish Physiol Biochem. 1993 Aug;12(2):111-7. doi: 10.1007/BF00004376. PMID: 24202690.
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Fish Physiol Biochem. 1993 Aug;12(2):111-7. doi: 10.1007/BF00004376.

Influence of nucleoside triphosphates, inorganic salts, NADH, catecholamines, and oxygen saturation on nitrite-induced oxidation of rainbow trout haemoglobin.

Fish physiology and biochemistry

F B Jensen

Affiliations

  1. Institute of Biology, Odense University, DK-5230, Odense M, Denmark.

PMID: 24202690 DOI: 10.1007/BF00004376

Abstract

Oxidation of rainbow trout haemoglobin (Hb) by nitrite proceeded via an initial lag phase followed by autocatalysis when the O2 saturation of the Hb was high. At low O2 saturations, the rate of methaemoglobin (metHb) formation was strongly reduced and autocatalysis was absent. Addition of adenosine triphosphate and guanosine triphosphate to oxyHb lowered the haemoglobin O2 affinity and O2 saturation and slowed down nitrite-induced metHb formation in a dose-dependent manner, the effect of GTP being larger than that of ATP. Reduced nicotinamide adenine dinucleotide (NADH) and the catecholamines adrenaline and noradrenaline did not affect O2 saturation in oxyHb solutions but significantly slowed down nitrite-induced metHb formation. Inorganic salts (NaCl, KCl, NaNO3) impeded the oxidation of oxyHb by nitrite in a manner that was dependent on salt concentration but independent of the type of salt. The mechanisms and physiological implication of the effects are discussed.

References

  1. Environ Health Perspect. 1987 Aug;73:147-51 - PubMed
  2. Biochim Biophys Acta. 1987 Jan 5;911(1):59-65 - PubMed
  3. J Comp Physiol B. 1987;157(2):145-52 - PubMed
  4. J Exp Zool. 1991 Oct;260(1):28-32 - PubMed
  5. Experientia. 1979 Jan 15;35(1):15-6 - PubMed
  6. Blood. 1990 Sep 1;76(5):1008-14 - PubMed
  7. Comp Biochem Physiol B. 1983;75(1):27-30 - PubMed
  8. Biochim Biophys Acta. 1982 Dec 20;709(2):187-93 - PubMed
  9. Anal Biochem. 1973 Sep;55(1):245-8 - PubMed
  10. J Exp Zool. 1987 Feb;241(2):269-73 - PubMed
  11. Annu Rev Physiol. 1988;50:161-79 - PubMed
  12. Clin Haematol. 1981 Feb;10(1):99-122 - PubMed

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