Semin Intervent Radiol. 2012 Dec;29(4):264-9. doi: 10.1055/s-0032-1330060.
Seminars in interventional radiology
Anuradha S Shenoy-Bhangle, Debra A Gervais
PMID: 24293799 PMCID: PMC3577625 DOI: 10.1055/s-0032-1330060
Fluid collections that are incompletely drained despite adequate catheter position, size, and number represent a minority of abscesses but a source of great frustration for patients, surgeons, and interventional radiologists. Drainage of such complex collections is known to be more effective with the adjunctive use of intracavitary fibrinolytic agents instilled via the drainage catheter. In this review article, we discuss the role of fibrinolytics specifically tissue plasminogen activator as explored by interventional radiologists in enhancing effective drainage of these complex abdominal and pelvic collections as well as complex pleural collections.
Keywords: abscess; empyema; interventional radiology; percutaneous drainage; thrombolytic therapy