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Malik A, Khan PA, Shujatullah F, et al. Rapid development of IRIS in the form of cryptococcal meningitis after beginning ART. Med Mycol Case Rep. 2012;1(1):56-8doi: 10.1016/j.mmcr.2012.07.002.
Malik, A., Khan, P. A., Shujatullah, F., Fatima, N., Shameem, M., & Siddiqui, A. (2012). Rapid development of IRIS in the form of cryptococcal meningitis after beginning ART. Medical mycology case reports, 1(1), 56-8. https://doi.org/10.1016/j.mmcr.2012.07.002
Malik, Abida, et al. "Rapid development of IRIS in the form of cryptococcal meningitis after beginning ART." Medical mycology case reports vol. 1,1 (2012): 56-8. doi: https://doi.org/10.1016/j.mmcr.2012.07.002
Malik A, Khan PA, Shujatullah F, Fatima N, Shameem M, Siddiqui A. Rapid development of IRIS in the form of cryptococcal meningitis after beginning ART. Med Mycol Case Rep. 2012 Aug 10;1(1):56-8. doi: 10.1016/j.mmcr.2012.07.002. eCollection 2012. PMID: 24371739; PMCID: PMC3854626.
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Med Mycol Case Rep. 2012 Aug 10;1(1):56-8. doi: 10.1016/j.mmcr.2012.07.002. eCollection 2012.

Rapid development of IRIS in the form of cryptococcal meningitis after beginning ART.

Medical mycology case reports

Abida Malik, Parvez A Khan, Fatima Shujatullah, Nazish Fatima, M Shameem, Azfar Siddiqui

Affiliations

  1. Department of Microbiology, J.N. Medical College and Hospital, A.M.U., Aligarh 202002, India.
  2. Department of Tuberculosis and Respiratory Diseases, J.N. Medical College and Hospital, A.M.U., Aligarh 202002, India.
  3. Department of Radiodiagnosis, J.N. Medical College and Hospital, A.M.U., Aligarh 202002, India.

PMID: 24371739 PMCID: PMC3854626 DOI: 10.1016/j.mmcr.2012.07.002

Abstract

Around one fourth of patients infected with human immunodeficiency virus (HIV) and given antiretroviral therapy (ART) experience inflammatory or cellular proliferative disease associated with a preexisting opportunistic infection. Many such infections are subclinical or quiescent before the patient begins ART. Cryptococcal immune reconstitution inflammatory syndrome may present as a clinical deterioration or new presentation of cryptococcal disease following initiation of antiretroviral therapy (ART) and is believed to be caused by recovery of Cryptococcus-specific immune responses. In the following report we present a case of expeditious developed IRIS in the form of cryptococcal meningitis.

Keywords: Anti-retroviral therapy (ART); Cryptococcal meningitis; Immune reconstitution inflammatory syndrome (IRIS)

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