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J Chem Ecol. 1984 Nov;10(11):1603-15. doi: 10.1007/BF00988428.

Possible chemical basis for histocompatibility-related mating preference in mice.

Journal of chemical ecology

F J Schwende, J W Jorgenson, M Novotny

Affiliations

  1. Department of Chemistry, Indiana University, 47405, Bloomington, Indiana.

PMID: 24318394 DOI: 10.1007/BF00988428

Abstract

High-resolution chromatographic profiles of urinary volatiles were quantitatively recorded and statistically evaluated for the female mice genetically differing in a small region of the major histocompatibility complex on the 17th chromosome. Both immature and estrogenized animals were evaluated. While there seem to be no specific volatile products of the histocompatibility genes, statistically significant differences were readily observed with the immature females of different haplotypes, involving the general range of secondary volatile metabolites. Their possible role in olfactory communication is discussed.

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