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Saudi J Anaesth. 2013 Oct;7(4):464-6. doi: 10.4103/1658-354X.121049.

Inadvertent intrathecal injection of large dose magnesium sulfate.

Saudi journal of anaesthesia

Atabak Najafi, Hooshang Akbari, Mohammad Reza Khajavi, Farhad Etezadi

Affiliations

  1. Department of Anesthesiology and Critical Care, Tehran University of Medical Sciences, Sina Hospital, Tehran, Iran.

PMID: 24348302 PMCID: PMC3858701 DOI: 10.4103/1658-354X.121049

Abstract

The case is a 35-year-old man who underwent spinal anesthesia for emergency strangulated inguinal hernia repair. About five minutes after 3 ml intrathecal drug injection, the patient suffered respiratory distress, bradycardia, hypotension and loss of consciousness. The patient was rapidly intubated and crystalloid infusion and epinephrine drip were established. Thereafter, he was admitted in intensive care unit. Search for the cause revealed us that 3 ml of magnesium sulfate (50%) was injected mistakenly for spinal anesthesia. Two days later, he was extubated and on the fifth day, he was discharged from the hospital without an obvious evidence of complication.

Keywords: Inadvertent intrathecal injection; magnesium sulfate; neurotoxicity; spinal anesthesia

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