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Mackowiak PA. Recycling metchnikoff: probiotics, the intestinal microbiome and the quest for long life. Front Public Health. 2013;1:52doi: 10.3389/fpubh.2013.00052.
Mackowiak, P. A. (2013). Recycling metchnikoff: probiotics, the intestinal microbiome and the quest for long life. Frontiers in public health, 152. https://doi.org/10.3389/fpubh.2013.00052
Mackowiak, Philip A. "Recycling metchnikoff: probiotics, the intestinal microbiome and the quest for long life." Frontiers in public health vol. 1 (2013): 52. doi: https://doi.org/10.3389/fpubh.2013.00052
Mackowiak PA. Recycling metchnikoff: probiotics, the intestinal microbiome and the quest for long life. Front Public Health. 2013 Nov 13;1:52. doi: 10.3389/fpubh.2013.00052. PMID: 24350221; PMCID: PMC3859987.
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Front Public Health. 2013 Nov 13;1:52. doi: 10.3389/fpubh.2013.00052.

Recycling metchnikoff: probiotics, the intestinal microbiome and the quest for long life.

Frontiers in public health

Philip A Mackowiak

Affiliations

  1. Medical Care Clinical Center, VA Maryland Health Care System , Baltimore, MD , USA ; Department of Medicine, University of Maryland School of Medicine , Baltimore, MD , USA.

PMID: 24350221 PMCID: PMC3859987 DOI: 10.3389/fpubh.2013.00052

Abstract

Over a century ago, Elie Metchnikoff theorized that health could be enhanced and senility delayed by manipulating the intestinal microbiome with host-friendly bacteria found in yogurt. His theory flourished for a time, then drifted to the fringe of medical practice before re-emerging in the mid-1990s as a concept worthy of mainstream medical attention. Metchnikoff also predicted the existence of bacterial translocation and anticipated theories linking chronic inflammation with the pathogenesis of atherosclerosis and other disorders of the aged.

Keywords: Lactobacilli; Metchnikoff; microbiome; phagocytes; senility

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