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Grotti Clemente AP, Molin Netto BD, Ganen Ad, et al. Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents. J Nutr Metab. 2013;2013:724781doi: 10.1155/2013/724781.
Grotti Clemente, A. P., Molin Netto, B. D., Ganen, A. d., Tock, L., Arisa Caranti, D., de Mello, M. T., Tufik, S., & Dâmaso, A. R. (2013). Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents. Journal of nutrition and metabolism, 2013724781. https://doi.org/10.1155/2013/724781
Grotti Clemente, Ana Paula, et al. "Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents." Journal of nutrition and metabolism vol. 2013 (2013): 724781. doi: https://doi.org/10.1155/2013/724781
Grotti Clemente AP, Molin Netto BD, Ganen Ad, Tock L, Arisa Caranti D, de Mello MT, Tufik S, Dâmaso AR. Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents. J Nutr Metab. 2013;2013:724781. doi: 10.1155/2013/724781. Epub 2013 Dec 07. PMID: 24381750; PMCID: PMC3872012.
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J Nutr Metab. 2013;2013:724781. doi: 10.1155/2013/724781. Epub 2013 Dec 07.

Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents.

Journal of nutrition and metabolism

Ana Paula Grotti Clemente, Bárbara Dal Molin Netto, Aline di Piano Ganen, Lian Tock, Danielle Arisa Caranti, Marco Túlio de Mello, Sergio Tufik, Ana R Dâmaso

Affiliations

  1. Post Graduate Program of Nutrition, Universidade Federal de São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), Rua Marselhesa, 630 Vila Clementino, 04020-060 São Paulo, SP, Brazil.
  2. Weigth Science Department, Rua Teodoro Sampaio, 744 Jardim Paulista, 05406-000 São Paulo, Brazil.
  3. Biosciences Department, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim 136, 11015-020 Santos, Brazil.
  4. Post Graduate Program of Nutrition, Universidade Federal de São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), Rua Marselhesa, 630 Vila Clementino, 04020-060 São Paulo, SP, Brazil ; Department of Psychobiology, Universidade Federal de São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), Rua Marselhesa, 630 Vila Clementino, 04020-060 São Paulo, SP, Brazil.
  5. Department of Psychobiology, Universidade Federal de São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), Rua Marselhesa, 630 Vila Clementino, 04020-060 São Paulo, SP, Brazil.
  6. Post Graduate Program of Nutrition, Universidade Federal de São Paulo, Escola Paulista de Medicina (UNIFESP-EPM), Rua Marselhesa, 630 Vila Clementino, 04020-060 São Paulo, SP, Brazil ; Biosciences Department, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim 136, 11015-020 Santos, Brazil ; Post Graduate Program of Interdisciplinary Health Sciences, Universidade Federal de São Paulo, Campus Baixada Santista, Rua Silva Jardim 136, 11015-020 Santos, Brazil.

PMID: 24381750 PMCID: PMC3872012 DOI: 10.1155/2013/724781

Abstract

Objectives. The present study aimed at determining cut-off points of visceral fat to predict NAFLD and analyzed metabolic disorders of obese adolescents. Methods. Cross-sectional study involved 165 obese adolescents ranged in age from 15 to 19 years. Glycemia, hepatic transaminases, lipid profile, and insulin resistance were analyzed. Visceral and subcutaneous fat were measured by ultrasound and body composition by plesthysmography. Results. The NAFLD adolescents had significantly higher values for body mass, BMI-for-age, BMI, total fat, waist circumference, and visceral fat when compared with non-NAFLD obese adolescents in both genders. Moreover, there were significant positive correlations between visceral fat with the variables BMI-for-age (r = 0.325,), TG (r = 0.277), AST (r = 0.509), ALT (r = 0.519), WC (r = 0.390), and visceral/subcutaneous ratio (r = 0.790) for NAFLD group. Total fat, triglycerides, and visceral fat were the independent predictors to NAFLD. Analysis of the ROC curves revealed cut-off points of visceral fat of 4.47 cm for girls and 4.21 cm for boys. Conclusions. The results may suggest that abdominal ultrasonography procedure may be a safe alternative method of assessing visceral adiposity aiming to be considered to the development of preventive and treatment strategies in obese individuals. This clinial trial is registered with ClinicalTrial.gov (NCT01358773).

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