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Mohtaram A, Afif M, Sghiri T, et al. Coexistence of Hodgkin's Lymphoma and Castleman's Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy. Case Rep Oncol Med. 2013;2013:487205doi: 10.1155/2013/487205.
Mohtaram, A., Afif, M., Sghiri, T., Rami, A., Latib, R., Kettani, F., Ben Ameur El Youbi, M., Boutayeb, S., Kebdani, T., Benjaafar, N., Aaribi, I., & Errihani, H. (2013). Coexistence of Hodgkin's Lymphoma and Castleman's Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy. Case reports in oncological medicine, 2013487205. https://doi.org/10.1155/2013/487205
Mohtaram, Amina, et al. "Coexistence of Hodgkin's Lymphoma and Castleman's Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy." Case reports in oncological medicine vol. 2013 (2013): 487205. doi: https://doi.org/10.1155/2013/487205
Mohtaram A, Afif M, Sghiri T, Rami A, Latib R, Kettani F, Ben Ameur El Youbi M, Boutayeb S, Kebdani T, Benjaafar N, Aaribi I, Errihani H. Coexistence of Hodgkin's Lymphoma and Castleman's Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy. Case Rep Oncol Med. 2013;2013:487205. doi: 10.1155/2013/487205. Epub 2013 Dec 05. PMID: 24381772; PMCID: PMC3870129.
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Case Rep Oncol Med. 2013;2013:487205. doi: 10.1155/2013/487205. Epub 2013 Dec 05.

Coexistence of Hodgkin's Lymphoma and Castleman's Disease: A Case Report with Successful Response to Chemotherapy and Radiotherapy.

Case reports in oncological medicine

Amina Mohtaram, Mohammed Afif, Tanae Sghiri, Amal Rami, Rachida Latib, Fouad Kettani, Meryam Ben Ameur El Youbi, Saber Boutayeb, Tayeb Kebdani, Noureddine Benjaafar, Imane Aaribi, Hassan Errihani

Affiliations

  1. Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
  2. Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
  3. Department of Radiology, National Institute of Oncology, Rabat, Morocco.
  4. Center of Pathology United Nations, Rabat, Morocco.

PMID: 24381772 PMCID: PMC3870129 DOI: 10.1155/2013/487205

Abstract

Background. Castleman's disease is a rare clinicopathological entity of unknown origin. Coexistence of Hodgkin's lymphoma and Castleman's disease is rare. We report a case of Hodgkin's disease of cervical lymph nodes in a patient previously diagnosed with Castleman's disease. Case Presentation. A 43-year-old man admitted in July 2009 for a right cervical pain with lymph node at the physician examination. He underwent a right adenectomy and histological studies showed typical features of Castleman's disease. Three years after, the patient consulted for increasing the volume of cervical lymph node. Clinical examination showed a right cervical lymph node of 3 cm. The computed tomography scan of chest, abdominal and pelvic was normal. Histological and immunohistochemical studies of cervical lymph node biopsy specimen were in favor of Castleman's disease associated with Hodgkin's disease. Reed-Sternberg cells were positive for CD15 and CD30. The patient received chemotherapy based on anthracyclines, bleomycin, vinblastine, and dacarbazine (ABVD) and radiotherapy with complete response. Conclusion. Prevalence of Hodgkin's lymphoma in Castleman's disease is more difficult to establish because of the low number of cases reported in the literature.

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