Display options
Share it on

Clin Colon Rectal Surg. 2013 Jun;26(2):122-7. doi: 10.1055/s-0033-1348051.

Laparoscopic surgery for crohn disease: a brief review of the literature.

Clinics in colon and rectal surgery

Cary B Aarons

Affiliations

  1. Division of Colon and Rectal Surgery, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.

PMID: 24436660 PMCID: PMC3709945 DOI: 10.1055/s-0033-1348051

Abstract

Crohn disease remains a challenging clinical entity, both medically and surgically. It frequently presents in early adulthood and imposes a lifetime exposure to chronic inflammation that can affect the entire gastrointestinal tract. Although the mainstay of therapy is treatment with immunomodulating drugs, ∼70 to 90% of patients with Crohn disease will ultimately require surgery. Furthermore, there are high rates of symptomatic recurrences that may also require surgical intervention over time. There is no definitive cure for Crohn disease and surgery is reserved for failed medical therapy or the complications of the disease, namely, obstruction, septic complications (abscess, perforation), and fistulas. However, the robust inflammatory environment during these periods is not always conducive to a minimally invasive surgical approach. Despite the inherent technical challenges, the literature has increasingly shown that laparoscopy for Crohn disease, in the appropriate setting, is feasible and safe. In fact, it offers many advantages, which are particularly beneficial to this subset of patients, such as fewer wound complications, a shortened hospital course, less tissue trauma and subsequent adhesion formation, and earlier resumption of oral intake and bowel function.

Keywords: Crohn disease; laparoscopy; minimally invasive surgery

References

  1. Dis Colon Rectum. 2007 May;50(5):576-85 - PubMed
  2. Gastroenterology. 2004 May;126(6):1504-17 - PubMed
  3. World J Gastroenterol. 2011 Mar 7;17(9):1116-25 - PubMed
  4. J Gastrointest Surg. 2007 Nov;11(11):1529-33 - PubMed
  5. J Gastrointest Surg. 2010 Apr;14(4):658-63 - PubMed
  6. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD006956 - PubMed
  7. Surg Endosc. 2012 Mar;26(3):777-82 - PubMed
  8. Arch Surg. 1997 Jan;132(1):41-4; discussion 45 - PubMed
  9. Ann Surg. 2006 Feb;243(2):143-9; discussion 150-3 - PubMed
  10. Gastroenterol Res Pract. 2012;2012:381017 - PubMed
  11. Colorectal Dis. 2011 Dec;13(12):1413-6 - PubMed
  12. Surg Endosc. 2010 Nov;24(11):2713-7 - PubMed
  13. Inflamm Bowel Dis. 2010 Aug;16(8):1382-6 - PubMed
  14. Surgery. 2008 Oct;144(4):622-7; discussion 627-8 - PubMed
  15. N Engl J Med. 2004 May 13;350(20):2050-9 - PubMed
  16. Dis Colon Rectum. 2008 Jun;51(6):818-26; discussion 826-8 - PubMed
  17. Dis Colon Rectum. 2012 Feb;55(2):140-6 - PubMed
  18. Br J Surg. 2010 Apr;97(4):563-8 - PubMed
  19. J Gastrointest Surg. 2009 Jul;13(7):1251-9 - PubMed
  20. Langenbecks Arch Surg. 2013 Jan;398(1):13-27 - PubMed
  21. Dis Colon Rectum. 2001 Jan;44(1):1-8; discussion 8-9 - PubMed
  22. Inflamm Bowel Dis. 2010 Nov;16(11):1940-6 - PubMed
  23. Dis Colon Rectum. 2006 Jan;49(1):58-63 - PubMed
  24. Clin Colon Rectal Surg. 2006 Feb;19(1):26-32 - PubMed

Publication Types