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Melloh M, Hodgson B, Carstens A, et al. Vascularized fibula strut graft used in neurofibromatosis type 1-related kyphosis: a case of almost complete reversal of deformity-induced tetraparesis. Evid Based Spine Care J. 2013;4(1):59-62doi: 10.1055/s-0033-1341599.
Melloh, M., Hodgson, B., Carstens, A., & Cornwall, J. (2013). Vascularized fibula strut graft used in neurofibromatosis type 1-related kyphosis: a case of almost complete reversal of deformity-induced tetraparesis. Evidence-based spine-care journal, 4(1), 59-62. https://doi.org/10.1055/s-0033-1341599
Melloh, Markus, et al. "Vascularized fibula strut graft used in neurofibromatosis type 1-related kyphosis: a case of almost complete reversal of deformity-induced tetraparesis." Evidence-based spine-care journal vol. 4,1 (2013): 59-62. doi: https://doi.org/10.1055/s-0033-1341599
Melloh M, Hodgson B, Carstens A, Cornwall J. Vascularized fibula strut graft used in neurofibromatosis type 1-related kyphosis: a case of almost complete reversal of deformity-induced tetraparesis. Evid Based Spine Care J. 2013 Apr;4(1):59-62. doi: 10.1055/s-0033-1341599. PMID: 24436700; PMCID: PMC3699244.
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Evid Based Spine Care J. 2013 Apr;4(1):59-62. doi: 10.1055/s-0033-1341599.

Vascularized fibula strut graft used in neurofibromatosis type 1-related kyphosis: a case of almost complete reversal of deformity-induced tetraparesis.

Evidence-based spine-care journal

Markus Melloh, Bruce Hodgson, Alan Carstens, Jon Cornwall

Affiliations

  1. Western Australian Institute for Medical Research (WAIMR), University of Western Australia, Nedlands, Western Australia, Australia.
  2. Department of Orthopaedic Surgery, Dunedin Public Hospital, Dunedin, New Zealand.
  3. Department of Anatomy, University of Otago, Dunedin, New Zealand.

PMID: 24436700 PMCID: PMC3699244 DOI: 10.1055/s-0033-1341599

Abstract

Study Design Case report. Objective The aim of this study is to describe a case of vascularized fibula strut graft implanted in the cervicothoracic spine of a patient with neurofibromatosis type 1-related progressive kyphosis. Methods A detailed history examination of the surgical procedures and the results of the follow-up after fibula strut graft implantation were performed. In addition, a review of the literature was conducted to access the incidence of similar cases with an almost complete reversal of a deformity-induced tetraparesis. Results A 37-year-old man with severe type 1 neurofibromatosis causing a collapsing kyphosis of the cervicothoracic spine presented in 2006 with progressive low cervical tetraparesis. Intervention included posterior stabilization (C5 to T5) which was extended to C3-T9 in 2008; however, the kyphosis continued to worsen. In 2009, a vascularized fibula strut graft was implanted between the inferior and superior endplates of C3 and T9. Over the following months, the patient gradually recovered motor strength and improved functional use of all limbs. In March 2011, lower limb (bilateral) and right arm strength was grade 5, with left arm strength being grade 4+. Conclusions This case report demonstrates the existence of a potential local option for the difficult problems of pseudoarthrosis, progressive spinal deformity, and cord compromise in patients with neurofibromatosis type 1-related kyphosis resulting in an almost complete reversal of deformity-induced tetraparesis.

Keywords: cervical spine; kyphosis; neurofibromatosis; tetraparesis

References

  1. J Bone Joint Surg Am. 1979 Jul;61(5):677-94 - PubMed
  2. J Spinal Disord. 1988;1(1):39-49 - PubMed
  3. Clin Orthop Relat Res. 1989 Aug;(245):29-42 - PubMed
  4. Spine (Phila Pa 1976). 1994 Jun 1;19(11):1264-70 - PubMed
  5. Spine (Phila Pa 1976). 2011 Aug 1;36(17):E1145-53 - PubMed
  6. Arq Neuropsiquiatr. 2008 Jun;66(2A):199-203 - PubMed
  7. Spine (Phila Pa 1976). 2009 Sep 15;34(20):2213-21 - PubMed
  8. Spine (Phila Pa 1976). 1985 Oct;10(8):710-6 - PubMed
  9. J Neurosurg Spine. 2011 Mar;14(3):356-66 - PubMed

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