Display options
Cite
Valduvieco I, Biete A, Rios I, et al. Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer. Rep Pract Oncol Radiother. 2013;18(4):214-9doi: 10.1016/j.rpor.2013.04.026.
Valduvieco, I., Biete, A., Rios, I., Llorente, R., Rovirosa, A., Pahisa, J., Vidal, L., Farrús, B., & Samper, P. (2013). Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer. Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 18(4), 214-9. https://doi.org/10.1016/j.rpor.2013.04.026
Valduvieco, Izaskun, et al. "Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer." Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology vol. 18,4 (2013): 214-9. doi: https://doi.org/10.1016/j.rpor.2013.04.026
Valduvieco I, Biete A, Rios I, Llorente R, Rovirosa A, Pahisa J, Vidal L, Farrús B, Samper P. Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer. Rep Pract Oncol Radiother. 2013 Jun 18;18(4):214-9. doi: 10.1016/j.rpor.2013.04.026. eCollection 2013. PMID: 24416556; PMCID: PMC3863248.
Copy Download .nbib Format: NLM
Share it on

Rep Pract Oncol Radiother. 2013 Jun 18;18(4):214-9. doi: 10.1016/j.rpor.2013.04.026. eCollection 2013.

Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Izaskun Valduvieco, Albert Biete, Iván Rios, Ricardo Llorente, Angels Rovirosa, Jaume Pahisa, Laura Vidal, Blanca Farrús, Pilar Samper

Affiliations

  1. Radiation Oncology Department, Institute of Haematology and Oncology (ICMHO), Gynecologic Oncology Unit, Hospital Clínic Universitari of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
  2. Gynecologic Oncology Unit, Hospital Clínic Universitari of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
  3. Radiation Oncology Department, Hospital Rey Juan Carlos, Madrid, Spain.

PMID: 24416556 PMCID: PMC3863248 DOI: 10.1016/j.rpor.2013.04.026

Abstract

BACKGROUND: The aim of our study is to evaluate the correlation between gynecological examination and magnetic resonance (MRI) findings for the assessment of local response in cervical cancer patients treated with radiotherapy/chemotherapy (RT/ChT).

PATIENTS AND METHODS: This study is a retrospective review of 75 consecutive cervical cancer patients from April 2004 to November 2009 treated with RT/ChT. Clinical and radiological data were subsequently analyzed. Patient's median age was 51 with a FIGO stage from Ib to IVb. Individualized RT/ChT was administered with a median dose of 45 Gy. Sixty-three patients received a complementary brachytherapy. Seventy-one patients received chemotherapy on a weekly basis. Gynecological exam was performed 3 months and 6 months after treatment and these findings were compared to MRI results at the same time.

STATISTIC ANALYSIS: We used the Spearman's Rho test to determine the correlation level between the clinical and radiological methods.

RESULTS: A correlation of 0.68 (60%) was observed between the clinical and MRI findings at 3 months with a further increase of up to 0.86 (82.6%) at 6 months. In the few cases with a poor correlation, the subsequent assessment and the natural history of the disease showed a greater value of the clinical exam as compared with the MRI findings.

CONCLUSIONS: Physical exam remains an essential tool to evaluate the local response to RT/ChT for cervical cancer. The optimal clinical radiological correlation found at 6 months after treatment suggests that the combination of gynecological examination and MRI are probably adequate in patient monitoring.

Keywords: Assessment of local response; Cervical cancer; Correlation clinical/radiological

References

  1. Strahlenther Onkol. 2012 Jul;188(7):568-75 - PubMed
  2. Gynecol Oncol. 2009 Sep;114(3):528-35 - PubMed
  3. Radiographics. 2003 Jul-Aug;23(4):969-81; discussion 981 - PubMed
  4. Rep Pract Oncol Radiother. 2012 Sep 05;17(6):332-8 - PubMed
  5. Strahlenther Onkol. 2011 Oct;187(10):611-8 - PubMed
  6. Eur J Nucl Med Mol Imaging. 2006 Dec;33(12):1399-407 - PubMed
  7. Radiology. 1988 Feb;166(2):333-40 - PubMed
  8. Int J Radiat Oncol Biol Phys. 1999 Oct 1;45(3):639-44 - PubMed
  9. J Gynecol Oncol. 2010 Mar;21(1):18-23 - PubMed
  10. Radiology. 1992 Jul;184(1):89-93 - PubMed
  11. J Nucl Med. 2003 Mar;44(3):347-52 - PubMed
  12. Int J Radiat Oncol Biol Phys. 2011 Dec 1;81(5):e707-12 - PubMed
  13. AJR Am J Roentgenol. 2003 Jun;180(6):1621-31 - PubMed
  14. Gynecol Oncol. 2012 Apr;125(1):256-62 - PubMed
  15. Magn Reson Med Sci. 2010;9(3):141-8 - PubMed
  16. Gynecol Oncol. 2008 Nov;111(2):213-20 - PubMed
  17. J Comput Assist Tomogr. 2011 Jan-Feb;35(1):102-7 - PubMed
  18. Radiol Med. 2011 Aug;116(5):766-80 - PubMed
  19. Cancer. 2008 Oct 15;113(8):2158-65 - PubMed
  20. Gynecol Oncol. 2011 Oct;123(1):110-5 - PubMed
  21. Int J Cancer. 2010 Dec 15;127(12):2893-917 - PubMed
  22. Diagn Interv Radiol. 2011 Mar;17(1):44-51 - PubMed

Publication Types