Display options
Cite
Nandakumar A, Kiruthika SE, Naveen K, et al. Pd(0)-catalyzed regio- and stereoselective cyclization of alkynes: selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles. Org Biomol Chem. 2014;12(6):876-80doi: 10.1039/c3ob42314j.
Nandakumar, A., Kiruthika, S. E., Naveen, K., & Perumal, P. T. (2014). Pd(0)-catalyzed regio- and stereoselective cyclization of alkynes: selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles. Organic & biomolecular chemistry, 12(6), 876-80. https://doi.org/10.1039/c3ob42314j
Nandakumar, Avanashiappan, et al. "Pd(0)-catalyzed regio- and stereoselective cyclization of alkynes: selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles." Organic & biomolecular chemistry vol. 12,6 (2014): 876-80. doi: https://doi.org/10.1039/c3ob42314j
Nandakumar A, Kiruthika SE, Naveen K, Perumal PT. Pd(0)-catalyzed regio- and stereoselective cyclization of alkynes: selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles. Org Biomol Chem. 2014 Feb 14;12(6):876-80. doi: 10.1039/c3ob42314j. PMID: 24357272.
Copy Download .nbib Format: NLM
Share it on

Org Biomol Chem. 2014 Feb 14;12(6):876-80. doi: 10.1039/c3ob42314j.

Pd(0)-catalyzed regio- and stereoselective cyclization of alkynes: selective synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles.

Organic & biomolecular chemistry

Avanashiappan Nandakumar, Selvarangam E Kiruthika, Kanagaraj Naveen, Paramasivan Thirumalai Perumal

Affiliations

  1. Organic Chemistry Division, CSIR-Central Leather Research Institute, Adyar, Chennai-600020, Tamil Nadu, India. [email protected].

PMID: 24357272 DOI: 10.1039/c3ob42314j

Abstract

Palladium-catalyzed highly regio- and stereoselective 6-exo-dig and 7-endo-dig cyclization of functionalized propargylic compounds has been developed for the synthesis of (E)-4-(isobenzofuran-1(3H)-ylidene)-1,2,3,4-tetrahydroisoquinolines and aze/oxepinoindoles.

Publication Types