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Mod Rheumatol. 2003 Mar;13(1):76-80. doi: 10.3109/s101650300012.

Two cases of acute respiratory distress syndrome resulting from adult-onset Still's disease.

Modern rheumatology

H Hagiyama, R Koike, K Nagasaka, Y Nonomura, J Nishio, T Nanki, H Kohsaka, T Kubota, N Miyasaka

Affiliations

  1. Department of Bioregulatory Medicine and Rheumatology, Tokyo Medical and Dental University Graduate School , 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519 , Japan.

PMID: 24387121 DOI: 10.3109/s101650300012

Abstract

Abstract Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown origin. Acute respiratory distress syndrome (ARDS) is a rare complication of AOSD, with only nine cases having been reported in the literature. Here, we describe two cases of AOSD complicated with ARDS that were successfully treated with immunosuppressive therapy, including corticosteroids. Although ARDS is a life-threatening complication in AOSD, early commencement of high-dose corticosteroids and mechanical ventilation improve the prognosis.

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