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Gladwin TE, Ter Mors-Schulte MH, Ridderinkhof KR, et al. Medial parietal cortex activation related to attention control involving alcohol cues. Front Psychiatry. 2013;4:174doi: 10.3389/fpsyt.2013.00174.
Gladwin, T. E., Ter Mors-Schulte, M. H., Ridderinkhof, K. R., & Wiers, R. W. (2013). Medial parietal cortex activation related to attention control involving alcohol cues. Frontiers in psychiatry, 4174. https://doi.org/10.3389/fpsyt.2013.00174
Gladwin, Thomas E, et al. "Medial parietal cortex activation related to attention control involving alcohol cues." Frontiers in psychiatry vol. 4 (2013): 174. doi: https://doi.org/10.3389/fpsyt.2013.00174
Gladwin TE, Ter Mors-Schulte MH, Ridderinkhof KR, Wiers RW. Medial parietal cortex activation related to attention control involving alcohol cues. Front Psychiatry. 2013 Dec 20;4:174. doi: 10.3389/fpsyt.2013.00174. eCollection 2013. PMID: 24391604; PMCID: PMC3868991.
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Front Psychiatry. 2013 Dec 20;4:174. doi: 10.3389/fpsyt.2013.00174. eCollection 2013.

Medial parietal cortex activation related to attention control involving alcohol cues.

Frontiers in psychiatry

Thomas E Gladwin, Mieke H J Ter Mors-Schulte, K Richard Ridderinkhof, Reinout W Wiers

Affiliations

  1. Addiction, Development, and Psychopathology (Adapt) Lab, Department of Psychology, University of Amsterdam , Amsterdam , Netherlands ; EPAN Lab, Behavioural Science Institute (BSI), Radboud University Nijmegen , Nijmegen , Netherlands.
  2. Addiction, Development, and Psychopathology (Adapt) Lab, Department of Psychology, University of Amsterdam , Amsterdam , Netherlands ; Department of Psychiatry, Academic Medical Center , Amsterdam , Netherlands.
  3. Department of Psychology, Amsterdam Center for the Study of Adaptive Control in Brain and Behavior (Acacia), University of Amsterdam , Amsterdam , Netherlands ; Cognitive Science Center Amsterdam, University of Amsterdam , Amsterdam , Netherlands.
  4. Addiction, Development, and Psychopathology (Adapt) Lab, Department of Psychology, University of Amsterdam , Amsterdam , Netherlands.

PMID: 24391604 PMCID: PMC3868991 DOI: 10.3389/fpsyt.2013.00174

Abstract

Automatic attentional engagement toward and disengagement from alcohol cues play a role in alcohol use and dependence. In the current study, social drinkers performed a spatial cueing task designed to evoke conflict between such automatic processes and task instructions, a potentially important task feature from the perspective of recent dual-process models of addiction. Subjects received instructions either to direct their attention toward pictures of alcoholic beverages, and away from non-alcohol beverages; or to direct their attention toward pictures of non-alcoholic beverages, and away from alcohol beverages. Instructions were varied per block. Activation in medial parietal cortex was found during "approach alcohol" versus "avoid-alcohol" blocks. This region is associated with the, possibly automatic, shifting of attention between stimulus features. Subjects thus appeared to shift attention away from certain features of alcoholic cues when attention had to be directed toward their location. Further, activation in voxels located close to this region was negatively correlated with riskier drinking behavior. A tentative interpretation of the results is that risky drinking may be associated with a reduced automatic tendency to shift attention away from potentially distracting task-irrelevant alcohol cues. Future study is needed to test this interpretation, and to further determine the role of medial posterior regions in automatic alcohol-related attentional processes in general.

Keywords: addiction; alcohol; attention; dual-process; fMRI; medial posterior cortex

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