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Cortez J, Gomes BC, Speidel A, et al. Mind the gap: Management of an emergent and threatening invasive fungal infection-a case report of rhino-orbital-cerebral and pulmonary mucormycosis. Med Mycol Case Rep. 2013;2:79-84doi: 10.1016/j.mmcr.2013.02.008.
Cortez, J., Gomes, B. C., Speidel, A., Peixoto, C., Selicka, E., Valente, C., Figueiredo, P., & Vieira, A. (2013). Mind the gap: Management of an emergent and threatening invasive fungal infection-a case report of rhino-orbital-cerebral and pulmonary mucormycosis. Medical mycology case reports, 279-84. https://doi.org/10.1016/j.mmcr.2013.02.008
Cortez, Joana, et al. "Mind the gap: Management of an emergent and threatening invasive fungal infection-a case report of rhino-orbital-cerebral and pulmonary mucormycosis." Medical mycology case reports vol. 2 (2013): 79-84. doi: https://doi.org/10.1016/j.mmcr.2013.02.008
Cortez J, Gomes BC, Speidel A, Peixoto C, Selicka E, Valente C, Figueiredo P, Vieira A. Mind the gap: Management of an emergent and threatening invasive fungal infection-a case report of rhino-orbital-cerebral and pulmonary mucormycosis. Med Mycol Case Rep. 2013 Mar 14;2:79-84. doi: 10.1016/j.mmcr.2013.02.008. eCollection 2013 Mar 14. PMID: 24432223; PMCID: PMC3885946.
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Med Mycol Case Rep. 2013 Mar 14;2:79-84. doi: 10.1016/j.mmcr.2013.02.008. eCollection 2013 Mar 14.

Mind the gap: Management of an emergent and threatening invasive fungal infection-a case report of rhino-orbital-cerebral and pulmonary mucormycosis.

Medical mycology case reports

Joana Cortez, Bruno Costa Gomes, Andrea Speidel, Conceição Peixoto, Elina Selicka, Cristina Valente, Paulo Figueiredo, António Vieira

Affiliations

  1. Infectious Diseases Department, Coimbra's Hospital Centre and University (Centro Hospitalar e Universitário de Coimbra), General Hospital, Coimbra 3041-801, Portugal.
  2. Neuroradiology Department, Coimbra's Hospital Centre and University (Centro Hospitalar e Universitário de Coimbra), General Hospital, Coimbra 3041-801, Portugal.
  3. Otorhinolaringology Department, Coimbra's Hospital Centre and University (Centro Hospitalar e Universitário de Coimbra), General Hospital, Coimbra 3041-801, Portugal.
  4. Infectious Diseases Department, Riga Eastern Clinical University Hospital, Infectology Centre of Latvia, Riga, Latvia.
  5. Pathology Department, Portuguese Oncology Institute (Instituto Português de Oncologia), Coimbra 3000-075, Portugal.

PMID: 24432223 PMCID: PMC3885946 DOI: 10.1016/j.mmcr.2013.02.008

Abstract

Mucormycosis is an emergent and threatening invasive fungal invasion underdiagnosed by clinicians due to lack of awareness and aspecific clinical picture. The authors describe a clinical case of a diabetic and cirrhotic patient who developed rhino-orbital-cerebral and pulmonary mucormycosis, non-responsive to treatment. Typical gaps in the management of this deadly disease are addressed. There is a strong need for novel therapies and an expectation that sponsors will recognize the critical need for randomized clinical trials.

Keywords: Delays; Diabetes; High mortality; Hyperbaric medicine; Mucormycosis; Randomized clinical trials

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