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Infect Dis Rep. 2010 Jun 15;2(1):e4. doi: 10.4081/idr.2010.e4. eCollection 2010 Feb 03.

Invasive fungal infections in endogenous Cushing's syndrome.

Infectious disease reports

Rafael Selbach Scheffel, José Miguel Dora, Letícia Schwerz Weinert, Valério Aquino, Ana Luiza Maia, Luis Henrique Canani, Luciano Z Goldani

Affiliations

  1. Endocrine Division.
  2. Microbiology Unit of the Clinical Pathology Division, and.
  3. Infectious Diseases Unit, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

PMID: 24470886 PMCID: PMC3892578 DOI: 10.4081/idr.2010.e4

Abstract

Cushing's syndrome is a condition characterized by elevated cortisol levels that can result from either augmented endogenous production or exogenous administration of corticosteroids. The predisposition to fungal infections among patients with hypercortisolemia has been noted since Cushing's original description of the disease. We describe here a patient with endogenous Cushing's syndrome secondary to an adrenocortical carcinoma, who developed concomitant disseminated cryptococcosis and candidiasis in the course of his disease.

Keywords: Cushing's disease; Cushing's syndrome; aspergillosis; candidemia; cryptococcosis; fungal infections; histoplasmosis; hypercortisolemia; mycosis.; pneumocystosis; scedosporiosis

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