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J Res Med Sci. 2013 Oct;18(10):827-32.

Preoperative carbohydrate nutrition reduces postoperative nausea and vomiting compared to preoperative fasting.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Neslihan Yilmaz, Nedim Cekmen, Ferruh Bilgin, Ela Erten, Mehmet Özhan Ozhan, Ahmet Coşar

Affiliations

  1. Gülhane Medical Faculty, Department of Anesthesiology and Reanimation, Ankara, Turkey.
  2. Güven Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey.
  3. TDV 29 Mayis Hospital, Department of Anesthesiology and Reanimation, Ankara, Turkey.

PMID: 24497851 PMCID: PMC3897064

Abstract

BACKGROUND: The aim of this prospective, randomized, single-blinded study was to compare the effects of a carbohydrate drink 400 mL given 2 h before the surgery with preoperative overnight fasting on the gastric pH and residual volume, postoperative nausea and vomiting (PONV) and antiemetic consumption in patients undergoing laparoscopic cholecystectomy.

MATERIALS AND METHODS: Forty American Society of Anesthesiologists physical status I-II patients who underwent elective laparoscopic cholecystectomy. Randomized, prospective, controlled study, Gulhane Medical Faculty and Guven Hospital Department of Anesthesiology and Reanimation. Patients were randomly assigned into two groups: Pre-operative carbohydrate drink group (group C, n = 20) and preoperative fasting group (group F, n = 20). Group C was given a 400 mL carbohydrate drink 2 h before to the surgery. The patients of group F were fasted 8 h before the surgery. Both groups were operated under general anesthesia with volatile anesthetics.

RESULTS: Hemodynamic parameters, demographic data, gastric acidity and residual volumes were similar for both groups. No complications were observed. PONV and antiemetic consumption was lower in group C compared to group F (P = 0.001). Patient's satisfaction was higher in group C (P < 0.001).

CONCLUSION: This study showed that pre-operative carbohydrate drink may be used safely and also improves patient's satisfaction and comfort in patients undergoing laparoscopic cholecystectomy.

Keywords: Laparoscopic cholecystectomy; post-operative nausea and vomiting; pre-operative carbohydrate nutrition; pre-operative fasting

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