Chem Heterocycl Compd (N Y). 2012 Mar 01;47(12):1516-1526. doi: 10.1007/s10593-012-0942-1.
Chemistry of heterocyclic compounds
D Chernyak, V Gevorgyan
PMID: 24501430 PMCID: PMC3910007 DOI: 10.1007/s10593-012-0942-1
Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this cascade transformation, which proceeds through an S
Keywords: allenes; cycloisomerization; indolizines; propargyl mesylates; synthetic methods