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Clin Epidemiol. 2014 Jan 30;6:61-70. doi: 10.2147/CLEP.S54237. eCollection 2014.

Patient-reported health as a prognostic factor for adverse events following percutaneous coronary intervention.

Clinical epidemiology

Karin Biering, Hans Erik Bøtker, Troels Niemann, Niels Henrik Hjollund

Affiliations

  1. Department of Occupational Medicine, Regional Hospital West Jutland, Herning, Denmark.
  2. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark.
  3. Department of Cardiology, Regional Hospital West Jutland, Herning, Denmark.
  4. WestChronic, Regional Hospital West Jutland, Herning, Denmark ; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.

PMID: 24511242 PMCID: PMC3915019 DOI: 10.2147/CLEP.S54237

Abstract

OBJECTIVE: A relation may exist between self-reported health and adverse events in coronary heart disease. Previous studies have been vulnerable to possible selection bias. In the study reported here, we examined the association between self-rated health and adverse events in terms of cardiac events, cardiac readmissions, and all-cause mortality in a complete cohort of patients treated with percutaneous coronary intervention (PCI).

STUDY DESIGN AND SETTING: A cohort of patients with coronary heart disease treated with PCI was followed up with questionnaires 4 weeks after PCI to measure self-rated health and in registers to identify adverse events. Of 1,752 eligible patients under 67 years, 26 died during the first 4 weeks. A total of 224 patients were excluded from the analysis because they were readmitted with a cardiac diagnosis before answering the first questionnaire. We received complete SF-12 Health Survey component summaries from 984 of the remaining 1,502 patients. We used multiple imputation to establish a complete cohort, including nonrespondents.

RESULTS: During follow-up, 83 patients died, 220 patients experienced a new cardiac event, and 526 patients experienced a hospital readmission related to coronary heart disease. Poor self-rated health was related to cardiac events, cardiac readmission, and all-cause mortality. The associations were stronger for all-cause mortality than for events and readmissions. Physical health was more important than mental health, but both revealed an exposure-response pattern.

CONCLUSION: Poor self-reported health within 4 weeks of PCI was associated with adverse outcomes during up to 5 years' follow-up.

Keywords: SF-12 adverse events; coronary heart disease; mortality; multiple imputation; patient-reported outcomes

References

  1. J Intern Med. 2008 Feb;263(2):203-11 - PubMed
  2. Stat Med. 2011 Feb 20;30(4):377-99 - PubMed
  3. Scand J Public Health. 2007;35(5):497-502 - PubMed
  4. J Health Psychol. 2001 Dec;6(6):707-11 - PubMed
  5. J Chronic Dis. 1987;40(5):373-83 - PubMed
  6. Value Health. 2004 Sep-Oct;7 Suppl 1:S4-8 - PubMed
  7. J Psychosom Res. 2008 Dec;65(6):587-93 - PubMed
  8. J Clin Epidemiol. 2002 Mar;55(3):306-9 - PubMed
  9. Am Heart J. 2009 Feb;157(2):208-18 - PubMed
  10. Eur J Cardiovasc Prev Rehabil. 2007 Aug;14(4):532-7 - PubMed
  11. Am J Cardiol. 2007 Sep 3;100(5A):3K-9K - PubMed
  12. J Health Soc Behav. 1997 Mar;38(1):21-37 - PubMed
  13. Am Heart J. 2010 Mar;159(3):471-6 - PubMed
  14. J Clin Epidemiol. 2004 Aug;57(8):837-42 - PubMed
  15. BMJ. 2009 Jun 29;338:b2393 - PubMed
  16. Clin Epidemiol. 2010 Aug 09;2:137-44 - PubMed
  17. Med Care. 2003 May;41(5):582-92 - PubMed
  18. Qual Life Res. 2011 May;20(4):559-67 - PubMed
  19. Int J Cardiol. 2013 Sep 1;167(5):2294-9 - PubMed
  20. Psychosomatics. 2007 Jul-Aug;48(4):331-7 - PubMed
  21. Dan Med Bull. 1999 Sep;46(4):354-7 - PubMed

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