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Caspian J Intern Med. 2014;5(1):35-9.

Clinical profile of classical Fever of unknown origin (FUO).

Caspian journal of internal medicine

Tanveer Mir, Gulam Nabi Dhobi, Ajaz Nabi Koul, Tajamul Saleh

Affiliations

  1. Department of Medicine, Division of Infectious Diseases, sheri-Kashmir Institute of Medical Sciences, India.

PMID: 24490012 PMCID: PMC3894469

Abstract

BACKGROUND: The etiology of fever of unknown origin (FUO) may differ from different countries. This study was conducted to evaluate the etiology of FUO in patients attending SKIMS, a tertiary care teaching hospital, at Srinagar, Kashmir, India.

METHODS: From July 2010 to September 2012, this study was done to examine the profile of patients with FUO. The classic FUO was defined as three outpatient visits or three days in the hospital without elucidation of cause of fever. Infectious agents, collagen vascular diseases and hematological malignancies as well as other etiologies were investigated when appropriate. The data were collected and analyzed.

RESULTS: A total of 91 cases (62 males and 29 females), with age ranging from 16 to 80 years were investigated. The mean duration of fever before hospitalization was 26±4 days. The etiology of FUO was delineated in (66%) of cases, whereas, (25%) remained undiagnosed. Most common group of FUO was that of infectious diseases (44%) followed by collagen vascular diseases and malignancies (12 % each). Amongst the infection group, brucellosis and salmonellosis comprised the majority of cases (25% each).

CONCLUSION: Infections are the most common cause of FUO followed by collagen vascular diseases in our region.

Keywords: Classical; Collagen vascular diseases.; Fever of unknown origin; Infectious diseases

References

  1. Medicine (Baltimore). 1961 Feb;40:1-30 - PubMed
  2. Arch Intern Med. 1992 Jan;152(1):51-5 - PubMed
  3. Medicine (Baltimore). 1982 Sep;61(5):269-92 - PubMed
  4. Tex Med. 1977 Jul;73(7):56-9 - PubMed
  5. Ann Saudi Med. 2010 Jul-Aug;30(4):289-94 - PubMed
  6. Rev Invest Clin. 2005 Nov-Dec;57(6):762-9 - PubMed
  7. Trop Doct. 1996 Oct;26(4):169-70 - PubMed
  8. Indian J Med Sci. 1999 Dec;53(12):535-44 - PubMed
  9. Postgrad Med J. 1988 Mar;64(749):209-12 - PubMed
  10. Postgrad Med J. 1992 Nov;68(805):884-7 - PubMed
  11. Arch Intern Med. 2003 May 12;163(9):1033-41 - PubMed
  12. Postgrad Med J. 2000 Oct;76(900):655-6 - PubMed
  13. Medicine (Baltimore). 2007 Jan;86(1):26-38 - PubMed
  14. Trop Geogr Med. 1992 Jan;44(1-2):32-6 - PubMed
  15. Medicine (Baltimore). 1997 Nov;76(6):392-400 - PubMed
  16. J Indian Med Assoc. 2000 Apr;98(4):170-1 - PubMed
  17. J Postgrad Med. 2001 Apr-Jun;47(2):104-7 - PubMed

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