Display options
Share it on

Iran Red Crescent Med J. 2013 Dec;15(12):e16617. doi: 10.5812/ircmj.16617. Epub 2013 Dec 05.

Measurement of colonic transit time based on radio opaque markers in patients with chronic idiopathic constipation; a cross-sectional study.

Iranian Red Crescent medical journal

Hazhir Saberi, Nastaran Asefi, Amir Keshvari, Shahram Agah, Mohsen Arabi, Hoda Asefi

Affiliations

  1. Department of Radiology, Tehran University of Medical Sciences, Tehran, IR Iran.
  2. Department of Surgery, Tehran University of Medical Sciences, Tehran, IR Iran.
  3. Department of Gastroenterology, Rasool Akram Hospital, Tehran, IR Iran.
  4. Department of Internal Medicine, Rasool Akram Hospital, Tehran, IR Iran.

PMID: 24693400 PMCID: PMC3955515 DOI: 10.5812/ircmj.16617

Abstract

BACKGROUND: Constipation is one of the most common gastrointestinal disorders particularly in industrialized countries. Incidence of constipation varies from 3.4 % to 27.2% in different societies. Increase in urban population, industrialization of communities, changes in behavioral and nutritional habits and inactivity have increased the number of patients suffering from constipation.

OBJECTIVES: The aim of the study was to measure colonic transit time in patients with chronic idiopathic constipation.

PATIENTS AND METHODS: Fifty-two patients with chronic idiopathic constipation (according to ROME III criteria) were selected. Patients with diabetes mellitus, hypothyroidism, and hypoparathyroidism were excluded. Each patient took a capsule containing ten 1-3 mm long angiographic guide daily for 6 days. Abdominal x-ray was performed on the seventh day. Remaining markers in each segment were counted and segmental and total colonic transit time was calculated. The analysis was performed by SPSS version 18. In all tests, a P-value less than 0.05 was considered statistically significant.

RESULTS: The mean age of patients was 36.9 ± 10.1 years. 80.8 % of patients were female. The mean total colonic transit time was 40.8 ±35.1 hours. 34.6 % of patients and 36.5 % of them had prolonged total and segmental colonic transit time.

CONCLUSIONS: We found that prolonged total and segmental colonic transit time is common in patients with chronic idiopathic constipation.

Keywords: Constipation; Habits; Hypothyroidism

References

  1. Gastroenterology. 1992 Mar;102(3):895-901 - PubMed
  2. Ther Umsch. 1994 Mar;51(3):177-89 - PubMed
  3. Gastroenterology. 1989 Oct;97(4):932-7 - PubMed
  4. Ned Tijdschr Geneeskd. 1998 Feb 14;142(7):357-61 - PubMed
  5. Arq Gastroenterol. 2008 Jan-Mar;45(1):58-63 - PubMed
  6. Gastroenterol Clin Biol. 1994;18(2):141-4 - PubMed
  7. Gastroenterology. 1999 Mar;116(3):732-60 - PubMed
  8. Gut. 1985 Oct;26(10):1049-52 - PubMed
  9. Hepat Mon. 2013 May 16;13(5):e9844 - PubMed
  10. Iran J Radiol. 2012 Dec;10(1):45-7 - PubMed
  11. Hepat Mon. 2013 Aug 12;13(8):e11138 - PubMed
  12. Am J Gastroenterol. 1999 Dec;94(12):3530-40 - PubMed
  13. Med Clin (Barc). 1992 Feb 15;98(6):201-6 - PubMed
  14. Am J Gastroenterol. 1996 Jan;91(1):19-25 - PubMed
  15. Hepat Mon. 2013 Aug 12;13(8):e7070 - PubMed
  16. Clin Gastroenterol Hepatol. 2007 Sep;5(9):1053-8 - PubMed
  17. Gut. 1986 Jan;27(1):41-8 - PubMed
  18. Ochsner J. 2008 Spring;8(1):25-31 - PubMed
  19. Dig Dis Sci. 1987 Aug;32(8):841-5 - PubMed
  20. Tech Coloproctol. 2006 Dec;10(4):287-96 - PubMed
  21. AJR Am J Roentgenol. 2007 Aug;189(2):W56-9 - PubMed
  22. Dis Colon Rectum. 1997 Mar;40(3):273-9 - PubMed
  23. Gastroenterology. 1978 Oct;75(4):623-31 - PubMed
  24. Gastroenterology. 2006 Apr;130(5):1480-91 - PubMed
  25. Iran J Radiol. 2013 Jun;10(2):90-3 - PubMed
  26. Iran J Radiol. 2013 Sep;10(3):156-9 - PubMed
  27. J Pediatr Gastroenterol Nutr. 1998 Aug;27(2):138-42 - PubMed
  28. Iran J Radiol. 2011 Sep;8(2):83-7 - PubMed

Publication Types