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Liu QA, Shao CL, Gu YC, et al. Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus. J Agric Food Chem. 2014;62(14):3183-3191doi: 10.1021/jf500248z.
Liu, Q. A., Shao, C. L., Gu, Y. C., Blum, M., Gan, L. S., Wang, K. L., Chen, M., & Wang, C. Y. (2014). Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus. Journal of agricultural and food chemistry, 62(14), 3183-3191. https://doi.org/10.1021/jf500248z
Liu, Qing-Ai, et al. "Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus." Journal of agricultural and food chemistry vol. 62,14 (2014): 3183-3191. doi: https://doi.org/10.1021/jf500248z
Liu QA, Shao CL, Gu YC, Blum M, Gan LS, Wang KL, Chen M, Wang CY. Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus. J Agric Food Chem. 2014 Apr 09;62(14):3183-3191. doi: 10.1021/jf500248z. Epub 2014 Mar 25. PMID: 24635109.
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J Agric Food Chem. 2014 Apr 09;62(14):3183-3191. doi: 10.1021/jf500248z. Epub 2014 Mar 25.

Antifouling and Fungicidal Resorcylic Acid Lactones from the Sea Anemone-Derived Fungus Cochliobolus lunatus.

Journal of agricultural and food chemistry

Qing-Ai Liu, Chang-Lun Shao, Yu-Cheng Gu, Mathias Blum, Li-She Gan, Kai-Ling Wang, Min Chen, Chang-Yun Wang

Affiliations

  1. Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003, People's Republic of China.
  2. Jealott's Hill International Research Centre, Syngenta , Bracknell, Berkshire, RG42 6EY, United Kingdom.
  3. Institute of Modern Chinese Medicine, College of Pharmaceutical Sciences, Zhejiang University , Hangzhou 310058, People's Republic of China.

PMID: 24635109 DOI: 10.1021/jf500248z

Abstract

Three new 14-membered resorcylic acid lactones, cochliomycins D-F, 1-3, and eight known analogues, 4-11, were isolated from the sea anemone-derived fungus Cochliobolus lunatus. Compounds 1-4 are diastereomers differing from each other by the absolute configurations of the 4',5'-diol chiral centers. The absolute configurations of 1-4 were established by the CD exciton chirality method and TDDFT ECD calculations. In antifouling assays, 1, 3-6, and 6a exhibited potent antifouling activities against the larval settlement of the barnacle Balanus amphitrite at nontoxic concentrations, with EC

Keywords: Cochliobolus lunatus; antifouling activity; fungicidal activity; resorcylic acid lactone; whole-plant assay

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