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Zhao D, Wang T, Shen Q, et al. n-Bu₄NI-catalyzed selective dual amination of sp³ C-H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale. Chem Commun (Camb). 2014;50(33):4302-4doi: 10.1039/c4cc01444h.
Zhao, D., Wang, T., Shen, Q., & Li, J. X. (2014). n-Bu₄NI-catalyzed selective dual amination of sp³ C-H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale. Chemical communications (Cambridge, England), 50(33), 4302-4. https://doi.org/10.1039/c4cc01444h
Zhao, Dan, et al. "n-Bu₄NI-catalyzed selective dual amination of sp³ C-H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale." Chemical communications (Cambridge, England) vol. 50,33 (2014): 4302-4. doi: https://doi.org/10.1039/c4cc01444h
Zhao D, Wang T, Shen Q, Li JX. n-Bu₄NI-catalyzed selective dual amination of sp³ C-H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale. Chem Commun (Camb). 2014 Apr 28;50(33):4302-4. doi: 10.1039/c4cc01444h. PMID: 24637953.
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Chem Commun (Camb). 2014 Apr 28;50(33):4302-4. doi: 10.1039/c4cc01444h.

n-Bu₄NI-catalyzed selective dual amination of sp³ C-H bonds: oxidative domino synthesis of imidazo[1,5-c]quinazolines on a gram-scale.

Chemical communications (Cambridge, England)

Dan Zhao, Teng Wang, Qi Shen, Jian-Xin Li

Affiliations

  1. State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China. [email protected].

PMID: 24637953 DOI: 10.1039/c4cc01444h

Abstract

An n-Bu4NI catalyzed domino reaction that involves selective dual amination of sp(3) C-H bonds has been developed. The protocol affords a facile and efficient approach to the synthesis of imidazo[1,5-c]quinazolines under mild conditions.

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