Cancer Manag Res. 2014 Mar 04;6:105-17. doi: 10.2147/CMAR.S32380. eCollection 2014.
Cancer management and research
Kenny A Rodriguez-Wallberg, Kutluk Oktay
PMID: 24623991 PMCID: PMC3949560 DOI: 10.2147/CMAR.S32380
The majority of children, adolescents, and young adults diagnosed with cancer today will become long-term survivors. The threat to fertility that cancer treatments pose to young patients cannot be prevented in many cases, and thus research into methods for fertility preservation is developing, aiming at offering cancer patients the ability to have biologically related children in the future. This paper discusses the current status of fertility preservation methods when infertility risks are related to surgical oncologic treatments, radiation therapy, or chemotherapy. Several scientific groups and societies have developed consensus documents and guidelines for fertility preservation. Decisions about fertility and imminent potentially gonadotoxic therapies must be made rapidly. Timely and complete information on the impact of cancer treatment on fertility and fertility preservation options should be presented to all patients when a cancer treatment is planned.
Keywords: cancer; cancer survival; cryopreservation; fertility preservation; fertility-sparing surgery; ovarian tissue transplantation; quality of life