Display options
Share it on

Korean J Anesthesiol. 2014 Mar;66(3):240-3. doi: 10.4097/kjae.2014.66.3.240. Epub 2014 Mar 28.

Epidural hematoma after thoracic epidural analgesia in a patient treated with ketorolac, mefenamic acid, and naftazone: a case report.

Korean journal of anesthesiology

Dae Geun Jeon, Jae Gyok Song, Seok-Kon Kim, Juri Kim

Affiliations

  1. Department of Anesthesiology and Pain Medicine, Dankook University College of Medicine, Cheonan, Korea.

PMID: 24729848 PMCID: PMC3983422 DOI: 10.4097/kjae.2014.66.3.240

Abstract

A 26-year-old male undergoing thoracotomy and bleeding control received a preoperative thoracic epidural for postoperative analgesia. On the fifth postoperative day, paralysis of both lower limbs occurred and urgent magnetic resonance imaging showed massive anterior epidural hematoma. During laminectomy and decompression, platelet dysfunction was diagnosed and preoperative non-steroidal anti-inflammatory drugs medications were supposed to the cause of platelet dysfunction. After infusion of ten units of platelet concentrate, coagulopathy was improved. We should be more careful to drugs with antiplatelet effect when using regional analgesia.

Keywords: Epidural hematoma; Ketorolac; Mefenamic acid; Naftazone; Platelet function

References

  1. J Anesth. 2008;22(3):290-3 - PubMed
  2. Reg Anesth Pain Med. 2010 Jan-Feb;35(1):64-101 - PubMed
  3. Int Anesthesiol Clin. 2001 Winter;39(1):51-61 - PubMed
  4. J Clin Pharm Ther. 2002 Dec;27(6):391-401 - PubMed
  5. J Clin Pharmacol. 1995 Mar;35(3):209-19 - PubMed
  6. Can J Anaesth. 2004 Jun-Jul;51(6):557-61 - PubMed
  7. Br J Anaesth. 2001 Dec;87(6):932-4 - PubMed
  8. J Pharm Pharmacol. 1996 Jun;48(6):566-72 - PubMed
  9. Platelets. 1999;10(1):66-70 - PubMed
  10. Masui. 2002 May;51(5):526-8 - PubMed
  11. Eur J Pharmacol. 2008 Oct 24;595(1-3):65-8 - PubMed
  12. Blood Rev. 2005 Mar;19(2):111-23 - PubMed

Publication Types