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Brembilla C, Lanterna LA, Bosisio M, et al. Spontaneous regression after extensive recurrence of a pediatric cervical spine aneurysmal bone cyst. Case Rep Oncol Med. 2014;2014:291674doi: 10.1155/2014/291674.
Brembilla, C., Lanterna, L. A., Bosisio, M., Gritti, P., Risso, A., Signorelli, A., & Biroli, F. (2014). Spontaneous regression after extensive recurrence of a pediatric cervical spine aneurysmal bone cyst. Case reports in oncological medicine, 2014291674. https://doi.org/10.1155/2014/291674
Brembilla, Carlo, et al. "Spontaneous regression after extensive recurrence of a pediatric cervical spine aneurysmal bone cyst." Case reports in oncological medicine vol. 2014 (2014): 291674. doi: https://doi.org/10.1155/2014/291674
Brembilla C, Lanterna LA, Bosisio M, Gritti P, Risso A, Signorelli A, Biroli F. Spontaneous regression after extensive recurrence of a pediatric cervical spine aneurysmal bone cyst. Case Rep Oncol Med. 2014;2014:291674. doi: 10.1155/2014/291674. Epub 2014 Jan 09. PMID: 24707421; PMCID: PMC3970344.
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Case Rep Oncol Med. 2014;2014:291674. doi: 10.1155/2014/291674. Epub 2014 Jan 09.

Spontaneous regression after extensive recurrence of a pediatric cervical spine aneurysmal bone cyst.

Case reports in oncological medicine

Carlo Brembilla, Luigi Andrea Lanterna, Michela Bosisio, Paolo Gritti, Andrea Risso, Antonio Signorelli, Francesco Biroli

Affiliations

  1. Department of Neurosurgery, Pope John XXIII Hospital, OMS Square No. 1, 24100 Bergamo, Italy.
  2. Department of Pediatrics, Pope John XXIII Hospital, OMS Square No. 1, 24100 Bergamo, Italy.
  3. Department of Anaesthesia and Intensive Care, Pope John XXIII Hospital, OMS Square No. 1, 24100 Bergamo, Italy.

PMID: 24707421 PMCID: PMC3970344 DOI: 10.1155/2014/291674

Abstract

Aneurysmal bone cyst is a pseudotumoral lesion. Complete resection prior to selective arterial embolization seems to be the treatment of choice for the more extensive and destructive lesions. In these cases maintaining stability of the cervical spine is critical. This can be very challenging in children and adolescents in whom the axial skeleton is still growing. In this case a young girl presented with a voluminous cervical aneurysmal bone cyst encaging both vertebral arteries and spinal cord. The lesion was treated with aggressive surgical resection, followed by cervical vertebral fusion with instrumentation. After nine months the patient referred no pain and no neurological deficit. MRI scans showed an extensive local recurrence. The family of the young girl refused any other therapy and any other followup. The patients returned to our attention after five years with no pain and neurological deficit. Cervical spine radiographs and MRI scans showed a complete regression of the extensive local recurrence. In the literature, the possibility of spontaneous regression of residual part or local recurrence is reported. The case of this young girl provided the chance to attend a spontaneous regression in an extensive recurrence of aneurismal bone cyst.

References

  1. Acta Neurochir (Wien). 1977;39(1-2):101-13 - PubMed
  2. J Bone Joint Surg Am. 1957 Jul;39-A(4):873-82 - PubMed
  3. Cancer. 1971 Sep;28(3):597-604 - PubMed
  4. An Esp Pediatr. 1987 Sep;27(3):190-4 - PubMed
  5. Clin Orthop Relat Res. 1999 Jun;(363):176-9 - PubMed
  6. Spine (Phila Pa 1976). 2001 Jan 1;26(1):27-35 - PubMed
  7. Radiology. 1998 Aug;208(2):369-73 - PubMed
  8. J Bone Joint Surg Am. 1985 Apr;67(4):527-31 - PubMed
  9. Arch Orthop Trauma Surg. 2007 Feb;127(2):105-14 - PubMed
  10. J Pediatr Orthop. 1997 Jul-Aug;17(4):440-3 - PubMed
  11. Pediatr Radiol. 2003 Jun;33(6):365-72 - PubMed
  12. J Pediatr Orthop. 1998 Mar-Apr;18(2):209-13 - PubMed
  13. J Pediatr Orthop B. 2004 Nov;13(6):389-94 - PubMed
  14. Eur Spine J. 2013 Mar;22(3):533-41 - PubMed
  15. Neurosurg Focus. 2003 Nov 15;15(5):E4 - PubMed
  16. Virchows Arch A Pathol Anat Histol. 1982;395(2):169-79 - PubMed
  17. J Pediatr Orthop B. 1998 Oct;7(4):286-92 - PubMed
  18. AJR Am J Roentgenol. 1995 Mar;164(3):573-80 - PubMed
  19. Cancer. 1992 Jun 15;69(12):2921-31 - PubMed
  20. Bull Hosp Joint Dis. 1950 Apr;11(1):3-13 - PubMed
  21. Skeletal Radiol. 1992;21(8):523-7 - PubMed
  22. Spine (Phila Pa 1976). 2009 Jan 1;34(1):E50-3 - PubMed
  23. Clin Orthop Relat Res. 1973 Nov-Dec;(97):52-63 - PubMed
  24. Neurosurg Clin N Am. 2008 Jan;19(1):41-7 - PubMed
  25. Spine (Phila Pa 1976). 2000 Jun 15;25(12):1589-92 - PubMed
  26. Spine (Phila Pa 1976). 1998 Mar 1;23(5):621-8 - PubMed
  27. J Clin Oncol. 2005 Sep 20;23(27):6756-62 - PubMed

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