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IEEE J Solid-State Circuits. 2013 May;48(5):1290-1301. doi: 10.1109/JSSC.2013.2245058.

A 256 pixel magnetoresistive biosensor microarray in 0.18μm CMOS.

IEEE journal of solid-state circuits

Drew A Hall, Richard S Gaster, Kofi Makinwa, Shan X Wang, Boris Murmann

Affiliations

  1. Stanford University, Stanford, CA 94305 USA.
  2. Delft University of Technology, Delft, The Netherlands.

PMID: 24761029 PMCID: PMC3993911 DOI: 10.1109/JSSC.2013.2245058

Abstract

Magnetic nanotechnologies have shown significant potential in several areas of nanomedicine such as imaging, therapeutics, and early disease detection. Giant magnetoresistive spin-valve (GMR SV) sensors coupled with magnetic nanotags (MNTs) possess great promise as ultra-sensitive biosensors for diagnostics. We report an integrated sensor interface for an array of 256 GMR SV biosensors designed in 0.18 μm CMOS. Arranged like an imager, each of the 16 column level readout channels contains an analog front- end and a compact ΣΔ modulator (0.054 mm

Keywords: GMR spin-valve; biochip; biosensor; magnetic biosensor; proteomics; sigma delta modulator

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