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Arias-Loste MT, Castro B, Rivero M, et al. Epidemiology of intrafamilial inflammatory bowel disease throughout Europe. Ann Gastroenterol. 2012;25(3):188-192
Arias-Loste, M. T., Castro, B., Rivero, M., & Crespo, J. (2012). Epidemiology of intrafamilial inflammatory bowel disease throughout Europe. Annals of gastroenterology, 25(3), 188-192.
Arias-Loste, Maria Teresa, et al. "Epidemiology of intrafamilial inflammatory bowel disease throughout Europe." Annals of gastroenterology vol. 25,3 (2012): 188-192.
Arias-Loste MT, Castro B, Rivero M, Crespo J. Epidemiology of intrafamilial inflammatory bowel disease throughout Europe. Ann Gastroenterol. 2012;25(3):188-192. PMID: 24713855; PMCID: PMC3959374.
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Ann Gastroenterol. 2012;25(3):188-192.

Epidemiology of intrafamilial inflammatory bowel disease throughout Europe.

Annals of gastroenterology

Maria Teresa Arias-Loste, Beatriz Castro, Montserrat Rivero, Javier Crespo

Affiliations

  1. Department of Gastroenterology and Hepatology, Marques de Valdecilla University Hospital, IFIMAV, Santander, Spain.

PMID: 24713855 PMCID: PMC3959374

Abstract

The incidence and prevalence of inflammatory bowel disease (IBD) have distinctly changed over the past decades throughout Europe. From former North-South and West-East risk gradients, nowadays, classic high-risk areas for IBD in North and West present more stable incidences whereas in formerly low-risk zones the incidence is rising. These changes cannot be explained by genetic modifications in IBD patients' background, which draws attention to the possible existence of potent environmental factors triggering this epidemiologic shift. Important lessons can be drawn from different European population-based studies assessing the influence of environmental factors in familial IBD that may impact on the outcome of the disease and the management of the patients and their relatives.

Keywords: environmental factors; epidemiology; familial aggregation; inflammatory bowel disease

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