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Pei X, Zhang J, Liu J. Clinical applications of nucleic acid aptamers in cancer. Mol Clin Oncol. 2014;2(3):341-348doi: 10.3892/mco.2014.255.
Pei, X., Zhang, J., & Liu, J. (2014). Clinical applications of nucleic acid aptamers in cancer. Molecular and clinical oncology, 2(3), 341-348. https://doi.org/10.3892/mco.2014.255
Pei, Xiaoyu, et al. "Clinical applications of nucleic acid aptamers in cancer." Molecular and clinical oncology vol. 2,3 (2014): 341-348. doi: https://doi.org/10.3892/mco.2014.255
Pei X, Zhang J, Liu J. Clinical applications of nucleic acid aptamers in cancer. Mol Clin Oncol. 2014 May;2(3):341-348. doi: 10.3892/mco.2014.255. Epub 2014 Feb 10. PMID: 24772298; PMCID: PMC3999129.
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Mol Clin Oncol. 2014 May;2(3):341-348. doi: 10.3892/mco.2014.255. Epub 2014 Feb 10.

Clinical applications of nucleic acid aptamers in cancer.

Molecular and clinical oncology

Xiaoyu Pei, Jun Zhang, Jie Liu

Affiliations

  1. Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040;
  2. Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040; ; Institute of Biomedical Sciences and Department of Immunology of Shanghai Medical School, Fudan University, Shanghai 200032, P.R. China.

PMID: 24772298 PMCID: PMC3999129 DOI: 10.3892/mco.2014.255

Abstract

Nucleic acid aptamers are small single-stranded DNA or RNA oligonucleotide segments, which bind to their targets with high affinity and specificity via unique three-dimensional structures. Aptamers are generated by an iterative

Keywords: aptamer; cancer diagnosis; cancer therapy; clinical application; systematic evolution of ligands by exponential enrichment

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