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Otsuka F, Joner M, Prati F, et al. Clinical classification of plaque morphology in coronary disease. Nat Rev Cardiol. 2014;11(7):379-89doi: 10.1038/nrcardio.2014.62.
Otsuka, F., Joner, M., Prati, F., Virmani, R., & Narula, J. (2014). Clinical classification of plaque morphology in coronary disease. Nature reviews. Cardiology, 11(7), 379-89. https://doi.org/10.1038/nrcardio.2014.62
Otsuka, Fumiyuki, et al. "Clinical classification of plaque morphology in coronary disease." Nature reviews. Cardiology vol. 11,7 (2014): 379-89. doi: https://doi.org/10.1038/nrcardio.2014.62
Otsuka F, Joner M, Prati F, Virmani R, Narula J. Clinical classification of plaque morphology in coronary disease. Nat Rev Cardiol. 2014 Jul;11(7):379-89. doi: 10.1038/nrcardio.2014.62. Epub 2014 Apr 29. PMID: 24776706.
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Nat Rev Cardiol. 2014 Jul;11(7):379-89. doi: 10.1038/nrcardio.2014.62. Epub 2014 Apr 29.

Clinical classification of plaque morphology in coronary disease.

Nature reviews. Cardiology

Fumiyuki Otsuka, Michael Joner, Francesco Prati, Renu Virmani, Jagat Narula

Affiliations

  1. Cardiovascular Pathology Inc., 19 Firstfield Road, Gaithersburg, MD 20878, USA.
  2. San Giovanni Addolorata Hospital and CLI Foundation, Via Amba Aradam, 8, Rome 00184, Italy.
  3. Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA.

PMID: 24776706 DOI: 10.1038/nrcardio.2014.62

Abstract

In published post-mortem pathological studies, more than two-thirds of acute coronary events are associated with the rupture of lipid-rich, voluminous, and outwardly remodelled plaques covered by attenuated and inflamed fibrous caps in the proximal part of coronary arteries. Superficial erosion of the plaques is responsible for most of the remaining events; the eroded plaques usually do not demonstrate much lipid burden, do not have thin fibrous caps, are not positively remodelled, and are not critically occlusive. Both noninvasive and invasive imaging studies have been performed to clinically define the plaque characteristics in acute coronary syndromes in an attempt to identify the high-risk plaque substrate susceptible to development of an acute coronary event. Optical coherence tomography (OCT)--an intravascular imaging modality with high resolution--can be used to define various stages of plaque morphology, which might allow its use for the identification of high-risk plaques vulnerable to rupture, and their amenability to pre-emptive interventional treatment. OCT might also be employed to characterize plaque pathology at the time of intervention, to provide a priori knowledge of the mechanism of the acute coronary syndrome and, therefore, to enable improved management of the condition.

References

  1. Circulation. 2005 Jan 18;111(2):143-9 - PubMed
  2. Eur Heart J. 2011 May;32(10):1251-9 - PubMed
  3. Sci Transl Med. 2011 May 25;3(84):84ra45 - PubMed
  4. Circulation. 1994 May;89(5):2462-78 - PubMed
  5. J Am Coll Cardiol. 2013 Mar 12;61(10):1041-51 - PubMed
  6. Curr Opin Cardiol. 2001 Sep;16(5):285-92 - PubMed
  7. Br Heart J. 1985 Apr;53(4):363-73 - PubMed
  8. Circ Cardiovasc Imaging. 2012 Jul;5(4):433-40 - PubMed
  9. Nat Med. 2011 Jul 10;17(8):1010-4 - PubMed
  10. Arterioscler Thromb Vasc Biol. 2007 May;27(5):986-9 - PubMed
  11. JACC Cardiovasc Imaging. 2012 Oct;5(10):1071-2 - PubMed
  12. J Thromb Haemost. 2012 Jun;10(6):985-91 - PubMed
  13. EuroIntervention. 2012 Dec 20;8(8):945-54 - PubMed
  14. JAMA. 1999 Mar 10;281(10):921-6 - PubMed
  15. JACC Cardiovasc Imaging. 2013 Mar;6(3):283-7 - PubMed
  16. J Am Coll Cardiol. 1985 Feb;5(2 Pt 1):342-6 - PubMed
  17. Med Interne. 1981 Oct-Dec;19(4):321-37 - PubMed
  18. J Am Coll Cardiol. 2012 Mar 20;59(12):1058-72 - PubMed
  19. J Am Coll Cardiol. 2007 Sep 4;50(10):933-9 - PubMed
  20. JACC Cardiovasc Interv. 2011 Dec;4(12):1257-70 - PubMed
  21. J Biomed Opt. 2012 Jul;17(7):070501 - PubMed
  22. Circulation. 2001 Feb 20;103(7):934-40 - PubMed
  23. N Engl J Med. 2003 Dec 11;349(24):2316-25 - PubMed
  24. Eur Heart J. 2013 Mar;34(10):719-28 - PubMed
  25. Circulation. 2003 Jan 7;107(1):113-9 - PubMed
  26. Circulation. 2002 Feb 26;105(8):939-43 - PubMed
  27. Circulation. 2008 Apr 15;117(15):2024-37 - PubMed
  28. Arterioscler Thromb Vasc Biol. 2000 May;20(5):1262-75 - PubMed
  29. Herz. 2001 Jun;26(4):239-44 - PubMed
  30. Eur Heart J. 2014 Mar;35(10):639-47 - PubMed
  31. Nat Med. 2007 May;13(5):532-4 - PubMed
  32. Am J Cardiol. 2010 Feb 1;105(3):318-22 - PubMed
  33. JACC Cardiovasc Imaging. 2013 Mar;6(3):288-9 - PubMed
  34. JACC Cardiovasc Imaging. 2013 Oct;6(10):1108-1114 - PubMed
  35. Arterioscler Thromb Vasc Biol. 2002 Oct 1;22(10):1642-8 - PubMed
  36. Nat Clin Pract Cardiovasc Med. 2008 Aug;5 Suppl 2:S2-10 - PubMed
  37. JACC Cardiovasc Imaging. 2011 Jul;4(7):810-3 - PubMed
  38. Eur Heart J. 2011 Nov;32(22):2814-23 - PubMed
  39. Circulation. 2002 Jan 22;105(3):297-303 - PubMed
  40. N Engl J Med. 2011 Jan 20;364(3):226-35 - PubMed
  41. J Am Coll Cardiol. 2004 Sep 1;44(5):972-9 - PubMed
  42. Cardiovasc Radiat Med. 2003 Oct-Dec;4(4):198-204 - PubMed
  43. N Engl J Med. 1997 May 1;336(18):1276-82 - PubMed
  44. N Engl J Med. 1987 May 28;316(22):1371-5 - PubMed
  45. JACC Cardiovasc Imaging. 2013 Oct;6(10):1124-1126 - PubMed
  46. N Engl J Med. 2005 Apr 21;352(16):1685-95 - PubMed
  47. J Am Coll Cardiol. 2013 Nov 5;62(19):1748-58 - PubMed
  48. Circulation. 2010 Nov 30;122(22):2288-300 - PubMed
  49. Heart. 2004 Dec;90(12):1385-91 - PubMed
  50. Circulation. 2005 Mar 29;111(12):1551-5 - PubMed
  51. J Am Coll Cardiol. 2014 Apr 1;63(12):1141-1144 - PubMed
  52. Eur Heart J. 2010 Feb;31(4):401-15 - PubMed
  53. Atherosclerosis. 2009 Feb;202(2):491-7 - PubMed
  54. Circulation. 1995 Sep 1;92(5):1355-74 - PubMed
  55. Circulation. 1996 Apr 1;93(7):1354-63 - PubMed
  56. Circulation. 2002 Sep 24;106(13):1640-5 - PubMed
  57. JACC Cardiovasc Imaging. 2011 Aug;4(8):894-901 - PubMed
  58. JACC Cardiovasc Imaging. 2012 Feb;5(2):169-77 - PubMed
  59. Circulation. 2008 Dec 2;118(23):2368-73 - PubMed

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