Display options
Cite
Hollier LP, Keelan JA, Hickey M, et al. Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development. Front Endocrinol (Lausanne). 2014;5:64doi: 10.3389/fendo.2014.00064.
Hollier, L. P., Keelan, J. A., Hickey, M., Maybery, M. T., & Whitehouse, A. J. (2014). Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development. Frontiers in endocrinology, 564. https://doi.org/10.3389/fendo.2014.00064
Hollier, Lauren P, et al. "Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development." Frontiers in endocrinology vol. 5 (2014): 64. doi: https://doi.org/10.3389/fendo.2014.00064
Hollier LP, Keelan JA, Hickey M, Maybery MT, Whitehouse AJ. Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development. Front Endocrinol (Lausanne). 2014 May 02;5:64. doi: 10.3389/fendo.2014.00064. eCollection 2014. PMID: 24829559; PMCID: PMC4014673.
Copy Download .nbib Format: NLM
Share it on

Front Endocrinol (Lausanne). 2014 May 02;5:64. doi: 10.3389/fendo.2014.00064. eCollection 2014.

Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development.

Frontiers in endocrinology

Lauren P Hollier, Jeffrey A Keelan, Martha Hickey, Murray T Maybery, Andrew J O Whitehouse

Affiliations

  1. Telethon Kids Institute, University of Western Australia , Subiaco, WA , Australia ; Neurocognitive Development Unit, School of Psychology, University of Western Australia , Crawley, WA , Australia.
  2. School of Women's and Infants' Health, University of Western Australia , Crawley, WA , Australia.
  3. Department of Obstetrics and Gynaecology, University of Melbourne , Parkville, VIC , Australia.
  4. Neurocognitive Development Unit, School of Psychology, University of Western Australia , Crawley, WA , Australia.
  5. Telethon Kids Institute, University of Western Australia , Subiaco, WA , Australia.

PMID: 24829559 PMCID: PMC4014673 DOI: 10.3389/fendo.2014.00064

Abstract

Accurately measuring hormone exposure during prenatal life presents a methodological challenge and there is currently no "gold standard" approach. Ideally, circulating fetal hormone levels would be measured at repeated time points during pregnancy. However, it is not currently possible to obtain fetal blood samples without significant risk to the fetus, and therefore surrogate markers of fetal hormone levels must be utilized. Umbilical cord blood can be readily obtained at birth and largely reflects fetal circulation in late gestation. This review examines the accuracy and biological interpretation of the measurement of androgens and estrogens in cord blood. The use of cord blood hormones to understand and investigate human development is then discussed.

Keywords: androgens; cord blood; estrogens; human development; prenatal

References

  1. Nicotine Tob Res. 2003 Jun;5(3):369-74 - PubMed
  2. Scand J Psychol. 2005 Dec;46(6):485-91 - PubMed
  3. Psychoneuroendocrinology. 2010 Sep;35(8):1235-44 - PubMed
  4. Child Dev. 1979 Sep;50(3):632-42 - PubMed
  5. Psychol Bull. 1995 Mar;117(2):250-70 - PubMed
  6. Maturitas. 2010 Sep;67(1):39-45 - PubMed
  7. Horm Behav. 2011 Aug;60(3):256-63 - PubMed
  8. J Clin Endocrinol Metab. 2007 Feb;92(2):405-13 - PubMed
  9. J Perinat Med. 2009;37(4):364-9 - PubMed
  10. Endocr Rev. 2011 Jun;32(3):317-55 - PubMed
  11. Physiol Res. 2014;63(1):115-26 - PubMed
  12. J Abnorm Child Psychol. 1987 Dec;15(4):629-50 - PubMed
  13. Clin Endocrinol Metab. 1986 May;15(2):259-78 - PubMed
  14. Clin Chem Lab Med. 2006;44(1):70-5 - PubMed
  15. PLoS One. 2013;8(4):e59991 - PubMed
  16. Endocr Rev. 1990 Feb;11(1):124-50 - PubMed
  17. Psychol Bull. 1996 May;119(3):422-47 - PubMed
  18. J Clin Endocrinol Metab. 2009 Oct;94(10):3714-20 - PubMed
  19. Cancer Epidemiol Biomarkers Prev. 2003 Nov;12(11 Pt 1):1268-70 - PubMed
  20. Cancer Sci. 2007 Jun;98(6):869-73 - PubMed
  21. Fertil Steril. 2005 Sep;84(3):701-10 - PubMed
  22. Twin Res Hum Genet. 2005 Apr;8(2):173-7 - PubMed
  23. Arch Sex Behav. 2009 Feb;38(1):6-15 - PubMed
  24. Cancer Epidemiol Biomarkers Prev. 2003 May;12(5):452-6 - PubMed
  25. Biol Neonate. 2001;79(3-4):150-6 - PubMed
  26. J Speech Lang Hear Res. 2007 Dec;50(6):1562-92 - PubMed
  27. J Steroid Biochem Mol Biol. 2014 Jan;139:201-22 - PubMed
  28. J Clin Endocrinol Metab. 1995 Jul;80(7):2217-21 - PubMed
  29. Dev Psychobiol. 1983 May;16(3):163-8 - PubMed
  30. Mol Cell Endocrinol. 2014 Jan 25;382(1):538-549 - PubMed
  31. Psychol Bull. 1995 Jul;118(1):55-107 - PubMed
  32. J Steroid Biochem Mol Biol. 2010 Aug;121(3-5):594-610 - PubMed
  33. Endocrinology. 2011 Jun;152(6):2409-15 - PubMed
  34. Hum Reprod Update. 2011 Mar-Apr;17(2):210-27 - PubMed
  35. Am J Obstet Gynecol. 1977 Sep 1;129(1):37-42 - PubMed
  36. Neuropsychology. 1999 Oct;13(4):590-7 - PubMed
  37. Endocrinology. 2011 Aug;152(8):2937-47 - PubMed
  38. Cancer Epidemiol Biomarkers Prev. 2014 Jun;23(6):946-52 - PubMed
  39. Front Neuroendocrinol. 2011 Apr;32(2):227-46 - PubMed
  40. J Genet Psychol. 1989 Mar;150(1):101-12 - PubMed
  41. PLoS One. 2012;7(8):e42827 - PubMed
  42. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Aug 15;855(2):249-54 - PubMed
  43. Dev Psychobiol. 1984 May;17(3):301-10 - PubMed
  44. J Steroid Biochem Mol Biol. 2010 Aug;121(3-5):491-5 - PubMed
  45. Child Dev. 2000 Mar-Apr;71(2):310-22 - PubMed
  46. Dev Psychobiol. 1988 Sep;21(6):567-74 - PubMed
  47. Breast Cancer Res. 2007;9(3):R29 - PubMed
  48. Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):224-31 - PubMed
  49. Horm Behav. 2004 Dec;46(5):663-9 - PubMed
  50. Br J Cancer. 2008 Oct 7;99(7):1161-4 - PubMed
  51. Early Hum Dev. 2011 Jun;87(6):407-14 - PubMed
  52. Ann Oncol. 2011 May;22(5):1102-1108 - PubMed
  53. Biol Neonate. 1994;65(5):287-94 - PubMed
  54. J Child Psychol Psychiatry. 2012 Jul;53(7):726-34 - PubMed
  55. Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1484-91 - PubMed
  56. Pediatrics. 2011 Jan;127(1):e197-201 - PubMed
  57. Biol Psychol. 2013 Feb;92(2):212-5 - PubMed
  58. J Clin Endocrinol Metab. 2013 Jun;98(6):2230-8 - PubMed
  59. Am J Obstet Gynecol. 1979 Jul 15;134(6):674-80 - PubMed
  60. Steroids. 2003 Dec;68(14):1173-8 - PubMed
  61. J Clin Endocrinol Metab. 2010 May;95(5):2180-6 - PubMed
  62. Cancer Causes Control. 2003 May;14(4):347-55 - PubMed
  63. Neuropsychology. 2001 Apr;15(2):165-73 - PubMed
  64. Endocr Rev. 2003 Apr;24(2):133-51 - PubMed
  65. J Speech Hear Disord. 1989 Nov;54(4):587-99 - PubMed
  66. J Autism Dev Disord. 2001 Feb;31(1):5-17 - PubMed
  67. J Pediatr Psychol. 1984 Jun;9(2):205-17 - PubMed
  68. Mol Autism. 2010 Jul 12;1(1):11 - PubMed
  69. Brain Cogn. 2002 Jun;49(1):1-12 - PubMed
  70. J Child Psychol Psychiatry. 2005 Feb;46(2):198-210 - PubMed
  71. Int J Gynaecol Obstet. 1993 Apr;41(1):37-41 - PubMed
  72. J Clin Endocrinol Metab. 1980 Dec;51(6):1235-8 - PubMed
  73. J Neurodev Disord. 2012 Oct 30;4(1):25 - PubMed
  74. Arch Gynecol Obstet. 1997;259(3):139-41 - PubMed
  75. Reprod Biomed Online. 2013 Jul;27(1):33-63 - PubMed
  76. Placenta. 1982 Jul-Sep;3(3):319-24 - PubMed
  77. Br J Psychol. 2009 Feb;100(Pt 1):1-22 - PubMed
  78. Int J Epidemiol. 2003 Jun;32(3):455-60 - PubMed

Publication Types