Display options
Cite
Dhakal P, Tsunoda N, Nakai R, et al. Post-Natal Dynamic Changes in Circulating Follicle-Stimulating Hormone, Luteinizing Hormone, Immunoreactive Inhibin, Progesterone, Testosterone and Estradiol-17β in Thoroughbred Colts until 6 Months of Age. J Equine Sci. 2011;22(1):9-15doi: 10.1294/jes.22.9.
Dhakal, P., Tsunoda, N., Nakai, R., Nagaoka, K., Nambo, Y., Sato, F., Taniyama, H., & Taya, K. (2011). Post-Natal Dynamic Changes in Circulating Follicle-Stimulating Hormone, Luteinizing Hormone, Immunoreactive Inhibin, Progesterone, Testosterone and Estradiol-17β in Thoroughbred Colts until 6 Months of Age. Journal of equine science, 22(1), 9-15. https://doi.org/10.1294/jes.22.9
Dhakal, Pramod, et al. "Post-Natal Dynamic Changes in Circulating Follicle-Stimulating Hormone, Luteinizing Hormone, Immunoreactive Inhibin, Progesterone, Testosterone and Estradiol-17β in Thoroughbred Colts until 6 Months of Age." Journal of equine science vol. 22,1 (2011): 9-15. doi: https://doi.org/10.1294/jes.22.9
Dhakal P, Tsunoda N, Nakai R, Nagaoka K, Nambo Y, Sato F, Taniyama H, Taya K. Post-Natal Dynamic Changes in Circulating Follicle-Stimulating Hormone, Luteinizing Hormone, Immunoreactive Inhibin, Progesterone, Testosterone and Estradiol-17β in Thoroughbred Colts until 6 Months of Age. J Equine Sci. 2011;22(1):9-15. doi: 10.1294/jes.22.9. Epub 2011 Apr 26. PMID: 24833982; PMCID: PMC4013995.
Copy Download .nbib Format: NLM
Share it on

J Equine Sci. 2011;22(1):9-15. doi: 10.1294/jes.22.9. Epub 2011 Apr 26.

Post-Natal Dynamic Changes in Circulating Follicle-Stimulating Hormone, Luteinizing Hormone, Immunoreactive Inhibin, Progesterone, Testosterone and Estradiol-17β in Thoroughbred Colts until 6 Months of Age.

Journal of equine science

Pramod Dhakal, Nobuo Tsunoda, Rie Nakai, Kentaro Nagaoka, Yasuo Nambo, Fumio Sato, Hiroyuki Taniyama, Kazuyoshi Taya

Affiliations

  1. Department of Basic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, Gifu 501-1193, Japan ; Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
  2. Shadai Corporation, Hokkaido 059-1432, Japan.
  3. Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
  4. Hidaka Training Research Center, Japan Racing Association, Hokkaido 057-0171, Japan.
  5. Department of Veterinary Pathology, Rakuno Gakuen University, Hokkaido 069-850, Japan.

PMID: 24833982 PMCID: PMC4013995 DOI: 10.1294/jes.22.9

Abstract

The aim of present study was to clarify the post-natal profile of follicle-stimulating hormone (FSH), luteinizing hormone (LH), immunoreactive (ir)-inhibin, progesterone, testosterone, and estradiol-17β, and their relationships in Thoroughbred colts. Six hundred and thirty-six colts were used for the study. Single plasma samples from each animal were harvested from the blood drawn through jugular venipuncture. The subjects were born with high amounts of progesterone, testosterone, and estradiol-17β, all of which dropped significantly and remained at lower levels till the end of 6 months. FSH decreased transiently after birth until day 12 and then gradually increased to peak at day 100 which then maintained in lesser levels towards the end of the studied period. LH was highest during birth which decreased until day 26 and then increased slowly to sub-birth levels up to day 90. Animals were born with high amounts of ir-inhibin. It dropped slowly and halved by day 20 and then decreased towards rest of the studied period. The increase in FSH is negatively correlated with the declining ir-inhibin levels. The early increase in FSH can be the indication of early post-natal maturation of the hypothalamic pituitary testicular axis that ultimately might be responsible for priming the testes for future development.

Keywords: FSH; Thoroughbred colt; ir-inhibin; post-natal; steroid hormones

References

  1. J Clin Endocrinol Metab. 2002 Jan;87(1):24-8 - PubMed
  2. J Endocrinol. 1993 Feb;136(2):235-43 - PubMed
  3. J Endocrinol. 1997 Nov;155(2):277-82 - PubMed
  4. Reprod Fertil Dev. 1996;8(8):1137-45 - PubMed
  5. J Equine Sci. 2011;22(1):9-15 - PubMed
  6. Biol Reprod. 2001 Jul;65(1):209-15 - PubMed
  7. Biol Reprod. 1997 Aug;57(2):347-53 - PubMed
  8. J Reprod Fertil Suppl. 1975 Oct;(23):531-6 - PubMed
  9. Biol Reprod. 2003 Jan;68(1):328-35 - PubMed
  10. J Androl. 2002 Mar-Apr;23(2):229-36 - PubMed
  11. Theriogenology. 2007 Sep 1;68(4):582-91 - PubMed
  12. J Endocrinol. 1993 Apr;137(1):15-9 - PubMed
  13. Endocrine. 2004 Oct;25(1):7-14 - PubMed
  14. Domest Anim Endocrinol. 2000 Jan;18(1):57-69 - PubMed
  15. Anim Reprod Sci. 2008 Apr;105(1-2):23-51 - PubMed
  16. Theriogenology. 2004 Jan 15;61(2-3):293-9 - PubMed
  17. J Reprod Fertil Suppl. 1995;49:393-407 - PubMed
  18. Anim Reprod Sci. 2003 Oct 15;78(3-4):259-70 - PubMed
  19. J Endocrinol. 1989 Sep;122(3):697-704 - PubMed

Publication Types