Epilepsy Curr. 2014 Jan;14(1):8-11. doi: 10.5698/1535-7511-14.s2.8.
Epilepsy currents
Adam L Hartman, J Helen Cross
PMID: 24955069 PMCID: PMC3966642 DOI: 10.5698/1535-7511-14.s2.8
Rasmussen syndrome affects previously normal people and forever changes their lives and the lives of their families. Although understood as a probable autoimmune condition, medical treatment remains limited and surgery remains the only cure, although with inevitable functional consequences. Difficulties remain in deciding on the optimal timing of surgery. Here, we review data available to aid clinicians faced with making the decision of when to recommend hemispherectomy. Not all patients have rapidly progressive disease, however, and such patients may benefit from immunomodulatory treatment. Thus, a patient's clinical course requires careful evaluation in order to identify those who would benefit most from early surgery.
