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Gastroenterol Hepatol Bed Bench. 2011;4(3):164-6.

Dubin-Johnson syndrome presenting after acute viral hepatitis.

Gastroenterology and hepatology from bed to bench

Farhad Lahmi, Mohammad Roshani, Katayoun Khosravi, Morteza Azizi, Seyed Reza Mohebbi, Mohammad Reza Zali

Affiliations

  1. Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical sciences Tehran, Iran.

PMID: 24834177 PMCID: PMC4017419

Abstract

Elevated serum level of bilirubin is a common manifestation which is occurred in several diseases. Hyperbilirubinemia can manifest either conjugated or unconjugated. Conjugated or direct hyperbilirubinemia usually are caused by hepatocellular diseases or cholestatic liver diseases. Merely conjugated hyperbilirubinemia is the main manifestation of two congenital syndromes, including Dubin-Johnson and rotor syndrome; however it can be seen in some patients with recurrent benign intrahepatic cholestasis. This article reports a patient with Dubin- Johuson syndrome as a benign and rare condition.

Keywords: Conjugated hyperbilirubinemia; Dubin-Johnson syndrome; Viral hepatitis

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