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Sale P, Stocchi F, Galafate D, et al. Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report. Front Hum Neurosci. 2014;8:207doi: 10.3389/fnhum.2014.00207.
Sale, P., Stocchi, F., Galafate, D., De Pandis, M. F., Le Pera, D., Sova, I., Galli, M., Foti, C., & Franceschini, M. (2014). Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report. Frontiers in human neuroscience, 8207. https://doi.org/10.3389/fnhum.2014.00207
Sale, Patrizio, et al. "Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report." Frontiers in human neuroscience vol. 8 (2014): 207. doi: https://doi.org/10.3389/fnhum.2014.00207
Sale P, Stocchi F, Galafate D, De Pandis MF, Le Pera D, Sova I, Galli M, Foti C, Franceschini M. Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report. Front Hum Neurosci. 2014 Apr 17;8:207. doi: 10.3389/fnhum.2014.00207. eCollection 2014. PMID: 24860459; PMCID: PMC4029018.
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Front Hum Neurosci. 2014 Apr 17;8:207. doi: 10.3389/fnhum.2014.00207. eCollection 2014.

Effects of robot assisted gait training in progressive supranuclear palsy (PSP): a preliminary report.

Frontiers in human neuroscience

Patrizio Sale, Fabrizio Stocchi, Daniele Galafate, Maria Francesca De Pandis, Domenica Le Pera, Ivan Sova, Manuela Galli, Calogero Foti, Marco Franceschini

Affiliations

  1. Department of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy.
  2. San Raffaele Cassino Cassino, Italy.
  3. Department of Neurorehabilitation, IRCCS San Raffaele Pisana Rome, Italy ; Dipartimento di Elettronica, Informazione e Bioingegneria-Politecnico di Milano Milano, Italy.
  4. Physical Rehabilitation Medicine Chair, Clinical Sciences and Translational Medicine DPT, Tor Vergata University Roma, Italy.

PMID: 24860459 PMCID: PMC4029018 DOI: 10.3389/fnhum.2014.00207

Abstract

BACKGROUND AND PURPOSE: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease clinically characterized by prominent axial extrapyramidal motor symptoms with frequent falls. Over the last years the introduction of robotic technologies to recover lower limb function has been greatly employed in the rehabilitative practice. This observational trial is aimed at investigating the changes in the main spatiotemporal following end-effector robot training in people with PSP.

METHOD: Pilot observational trial.

PARTICIPANTS: Five cognitively intact participants with PSP and gait disorders.

INTERVENTIONS: Patients were submitted to a rehabilitative program of robot-assisted walking sessions for 45 min, 5 times a week for 4 weeks.

MAIN OUTCOME MEASURES: The spatiotemporal parameters at the beginning (T0) and at the end of treatment (T1) were recorded by a gait analysis laboratory.

RESULTS: Robot training was feasible, acceptable and safe and all participants completed the prescribed training sessions. All patients showed an improvement in the gait spatiotemporal index (Mean velocity, Cadence, Step length, and Step width) (T0 vs. T1).

CONCLUSIONS: Robot training is a feasible and safe form of rehabilitation for cognitively intact people with PSP. The lack of side effects and the positive results in the gait parameter index in all patients support the recommendation to extend the trials of this treatment. Further investigation regarding the effectiveness of robot training in time is necessary.

TRIAL REGISTRATION: ClinicalTrials.gov NCT01668407.

Keywords: PSP; gait analysis; lower limb; progressive supranuclear palsy; robot

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