Display options
Cite
Rana SS, Bhasin DK, Sharma RK, et al. Do the morphological features of walled off pancreatic necrosis on endoscopic ultrasound determine the outcome of endoscopic transmural drainage?. Endosc Ultrasound. 2014;3(2):118-22doi: 10.4103/2303-9027.131039.
Rana, S. S., Bhasin, D. K., Sharma, R. K., Kathiresan, J., & Gupta, R. (2014). Do the morphological features of walled off pancreatic necrosis on endoscopic ultrasound determine the outcome of endoscopic transmural drainage?. Endoscopic ultrasound, 3(2), 118-22. https://doi.org/10.4103/2303-9027.131039
Rana, Surinder Singh, et al. "Do the morphological features of walled off pancreatic necrosis on endoscopic ultrasound determine the outcome of endoscopic transmural drainage?." Endoscopic ultrasound vol. 3,2 (2014): 118-22. doi: https://doi.org/10.4103/2303-9027.131039
Rana SS, Bhasin DK, Sharma RK, Kathiresan J, Gupta R. Do the morphological features of walled off pancreatic necrosis on endoscopic ultrasound determine the outcome of endoscopic transmural drainage?. Endosc Ultrasound. 2014 Apr;3(2):118-22. doi: 10.4103/2303-9027.131039. PMID: 24955341; PMCID: PMC4064159.
Copy Download .nbib Format: NLM
Share it on

Endosc Ultrasound. 2014 Apr;3(2):118-22. doi: 10.4103/2303-9027.131039.

Do the morphological features of walled off pancreatic necrosis on endoscopic ultrasound determine the outcome of endoscopic transmural drainage?.

Endoscopic ultrasound

Surinder Singh Rana, Deepak Kumar Bhasin, Ravi Kumar Sharma, Jeyashree Kathiresan, Rajesh Gupta

Affiliations

  1. Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012, India.
  2. School of Public Health, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012, India.
  3. Department of Surgery, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012, India.

PMID: 24955341 PMCID: PMC4064159 DOI: 10.4103/2303-9027.131039

Abstract

BACKGROUND AND OBJECTIVE: Endoscopic transmural drainage is an effective, but technically demanding treatment modality for walled off pancreatic necrosis (WOPN). The factors that determine the outcome of endoscopic treatment for WOPN have been infrequently studied. We aim to retrospectively correlate the morphological features of WOPN on endoscopic ultrasound (EUS) with the outcome of endoscopic transmural drainage.

PATIENTS AND METHODS: Over the last 3 years, 43 patients (36 males; mean age 36.04 ± 10.06 years) with symptomatic WOPN were treated by an attempted endoscopic drainage. The correlation between the morphological features of WOPN and the type of treatment offered as well as the number of endoscopic procedures undergone by the patient was assessed.

RESULTS: The mean size of WOPN was 9.95 ± 2.75 cm with <10%, 10-40% and >40% solid debris being present in 6, 33, and 4 patients, respectively. Patients with <10% necrotic debris needed only single session of endoscopic drainage, whereas patients with 10-40% solid debris needed two or more sessions. Patients with >40% solid debris either needed direct endoscopic debridement or surgical necrosectomy. The extent of necrosis correlated significantly (r = 0.703, P < 0.001) with the type of treatment received by the patient. With increasing size of the collection (r = 0.320, P = 0.047) and the amount of the solid debris (r = 0.800, P < 0.001), there was a significant increase in the number of endoscopic procedures required for successful outcome by the patient.

CONCLUSIONS: The morphological features of WOPN on EUS have important therapeutic implications with collections having large size and more solid debris needing more aggressive therapeutic method for the successful outcome.

Keywords: Acute pancreatitis; computed tomography; endoscopic ultrasound; walled off pancreatic necrosis

References

  1. Dig Endosc. 2013 Jan;25(1):47-52 - PubMed
  2. Gastrointest Endosc. 2011 Jul;74(1):74-80 - PubMed
  3. Gastrointest Endosc. 2009 May;69(6):1085-94 - PubMed
  4. Endoscopy. 2006 Sep;38(9):925-8 - PubMed
  5. Gastrointest Endosc. 2005 Jul;62(1):92-100 - PubMed
  6. J Gastroenterol Hepatol. 2013 Nov;28(11):1725-32 - PubMed
  7. Gut. 2009 Sep;58(9):1260-6 - PubMed
  8. Arch Surg. 1993 May;128(5):586-90 - PubMed
  9. Surg Endosc. 2011 Dec;25(12):3724-30 - PubMed

Publication Types