Int J Psychiatry Clin Pract. 2000;4(1):69-71. doi: 10.1080/13651500050518424.
International journal of psychiatry in clinical practice
J Wiersma A Honig Fpj Peters
PMID: 24927317 DOI: 10.1080/13651500050518424
We describe a case history of a 41-year-old woman who developed an allergic hepatitis with massive eosinophilia and elevated hepatic transaminases secondary to clomipramine, a tricyclic antidepressant (TCA) drug. Although drug-induced allergic hepatitis during tricyclic antidepressant therapy is very rare, one should consider this diagnosis in the case of (right-sided) abdominal pain and fever whenever a TCA is used, especially during the second month of treatment. (Int J Psych Clin Pract 2000; 4:69-71).
Keywords: Tricyclic Antidepressant Allergic Hepatitis Clomipramine Drug-INDUCED Hepatitis