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Florence AT. Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug Discov Today Technol. 2005;2(1):75-81doi: 10.1016/j.ddtec.2005.05.019.
Florence, A. T. (2005). Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug discovery today. Technologies, 2(1), 75-81. https://doi.org/10.1016/j.ddtec.2005.05.019
Florence, Alexander T. "Nanoparticle uptake by the oral route: Fulfilling its potential?." Drug discovery today. Technologies vol. 2,1 (2005): 75-81. doi: https://doi.org/10.1016/j.ddtec.2005.05.019
Florence AT. Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug Discov Today Technol. 2005;2(1):75-81. doi: 10.1016/j.ddtec.2005.05.019. PMID: 24981758.
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Drug Discov Today Technol. 2005;2(1):75-81. doi: 10.1016/j.ddtec.2005.05.019.

Nanoparticle uptake by the oral route: Fulfilling its potential?.

Drug discovery today. Technologies

Alexander T Florence

Affiliations

  1. Centre for Drug Delivery Research, The School of Pharmacy, University of London, London, UK WC1N 1AX. Electronic address:[email protected].

PMID: 24981758 DOI: 10.1016/j.ddtec.2005.05.019

Abstract

The absorption of nanoparticles from the gastrointestinal tract is discussed first from a recent historical perspective, emphasising the crucial parameters that influence uptake, such as particle diameter, the nature of the particle and any surface modification with ligands designed to interact with receptors to facilitate targeting to and uptake into cells. Post-absorptive events, including translocation processes, are suggested here to be as important as initial uptake into the epithelial cells or M-cells of the gut associated lymphoid tissue.:

© 2005 Elsevier Ltd . All rights reserved.

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