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J Oral Maxillofac Pathol. 2014 Jan;18(1):118-20. doi: 10.4103/0973-029X.131935.

An unusual case of epithelial-myoepithelial carcinoma of the parotid gland radiologically simulating a benign lesion.

Journal of oral and maxillofacial pathology : JOMFP

Shubhra Sharma, Sangeeta Patankar

Affiliations

  1. Department of Oral Pathology, Terna Dental College, Maharashtra, India.
  2. Yerala Medical Trust's Dental College, Navi Mumbai, Maharashtra, India.

PMID: 24959051 PMCID: PMC4065428 DOI: 10.4103/0973-029X.131935

Abstract

Epithelialmyoepithelial carcinoma (EMEC) is a rare low-grade malignant salivary gland neoplasm that most commonly occurs in the parotid gland but can also arise in minor salivary glands. Here, we present a case of EMEC in a 60-year-old male patient with a huge swelling in the left parotid gland region. Clinically and radiologically, it simulated a benign salivary gland neoplasm. However, fine-needle aspiration cytology and histologic examination revealed atypical myoepithelial cells in solid sheets or nests suggestive of epithelial-myoepithelial carcinoma. Diagnosis was further confirmed by positive immunohistochemical staining with calponin (CALP) and periodic acid-Schiff (PAS) for glycogen.

Keywords: Biphasic pattern; epithelial-myoepithelial carcinoma; parotid gland

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