Display options
Cite
Nunez L, Broome B, Pace T, et al. Treatment for Wear and Osteolysis in Well-Fixed Uncemented TKR. ISRN Orthop. 2013;2013:398298doi: 10.1155/2013/398298.
Nunez, L., Broome, B., Pace, T., & Harman, M. (2013). Treatment for Wear and Osteolysis in Well-Fixed Uncemented TKR. ISRN orthopedics, 2013398298. https://doi.org/10.1155/2013/398298
Nunez, Leah, et al. "Treatment for Wear and Osteolysis in Well-Fixed Uncemented TKR." ISRN orthopedics vol. 2013 (2013): 398298. doi: https://doi.org/10.1155/2013/398298
Nunez L, Broome B, Pace T, Harman M. Treatment for Wear and Osteolysis in Well-Fixed Uncemented TKR. ISRN Orthop. 2013 Feb 11;2013:398298. doi: 10.1155/2013/398298. eCollection 2013. PMID: 24959358; PMCID: PMC4045342.
Copy Download .nbib Format: NLM
Share it on

ISRN Orthop. 2013 Feb 11;2013:398298. doi: 10.1155/2013/398298. eCollection 2013.

Treatment for Wear and Osteolysis in Well-Fixed Uncemented TKR.

ISRN orthopedics

Leah Nunez, Brandon Broome, Tom Pace, Melinda Harman

Affiliations

  1. Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.
  2. Department of Bioengineering, Clemson University, Clemson, SC 29634, USA ; Steadman Hawkins Clinic of the Carolinas, Greenville, SC 29615, USA.
  3. Department of Bioengineering, Clemson University, Clemson, SC 29634, USA ; Department of Orthopaedics, USCSOM-Greenville, Greenville, SC 29208, USA.

PMID: 24959358 PMCID: PMC4045342 DOI: 10.1155/2013/398298

Abstract

Background. Traditionally, osteolysis around total knee replacements (TKRs) is treated with complete revision. In certain subsets, polyethylene insert exchange and bone grafting may be applicable. This study reports the clinical outcomes for selective bone grafting in patients with osteolysis without complete revision of the TKR. Methods. This retrospective study analyzes 10 TKRs (9 patients, 66.5 ± 6.1 years old) presenting with osteolysis and revised after 8.7 ± 1.9 years of in vivo function. At index TKR, all patients were implanted with uncemented prosthesis and modular polyethylene insert with anteroposterior articular constraint (Ultracongruent, Natural Knee II, Sulzer Medica). The surgical technique for treating the osteolysis included removal of necrotic bone tissue using curettage, filling of the defect with bone graft materials, and polyethylene insert exchange. Results. Patients have not exhibited any further complications associated with osteolysis after 5.1 ± 2.4 years of followup. Routine radiographic exams show total incorporation of the graft material into the previously lytic regions in all patients. Conclusion. In some TKRs with osteolysis and firmly fixed components, the removal of lytic tissue and subsequent defect filling with bone graft materials can be a viable solution. This case series shows complete resolution of osteolysis in all patients with no complications.

References

  1. J Bone Joint Surg Am. 2000 Apr;82(4):516-23 - PubMed
  2. Clin Orthop Relat Res. 2012 Jul;470(7):1869-78 - PubMed
  3. J Arthroplasty. 2007 Oct;22(7):987-92 - PubMed
  4. J Arthroplasty. 1997 Dec;12(8):896-903 - PubMed
  5. Acta Orthop. 2013 Feb;84(1):112-5 - PubMed
  6. Knee Surg Sports Traumatol Arthrosc. 2001 May;9(3):173-7 - PubMed
  7. J Bone Joint Surg Am. 1992 Jul;74(6):864-76 - PubMed
  8. Clin Orthop Relat Res. 1994 Dec;(309):33-43 - PubMed
  9. J Arthroplasty. 2005 Jan;20(1):35-41 - PubMed
  10. J Bone Joint Surg Br. 1992 May;74(3):393-7 - PubMed
  11. J Arthroplasty. 2001 Feb;16(2):239-42 - PubMed
  12. Clin Orthop Relat Res. 1995 Dec;(321):173-7 - PubMed
  13. J Bone Joint Surg Br. 1992 Jan;74(1):9-17 - PubMed
  14. Clin Orthop Relat Res. 2006 Nov;452:193-9 - PubMed
  15. J Bone Joint Surg Am. 2002 Jan;84(1):64-8 - PubMed
  16. J Arthroplasty. 1992 Dec;7(4):483-93 - PubMed
  17. Clin Orthop Relat Res. 2011 Jan;469(1):154-9 - PubMed
  18. Orthopedics. 2011 Mar 11;34(3):224 - PubMed
  19. Clin Orthop Relat Res. 2007 Nov;464:132-7 - PubMed
  20. J Biomed Mater Res. 1998 Winter;43(4):473-7 - PubMed
  21. Injury. 2007 Sep;38 Suppl 4:S13-21 - PubMed
  22. Orthop Rev. 1994 Apr;23(4):332-7 - PubMed
  23. J Bone Joint Surg Am. 1995 Nov;77(11):1700-7 - PubMed
  24. Clin Orthop Relat Res. 1989 Nov;(248):13-4 - PubMed
  25. J Arthroplasty. 2002 Sep;17(6):752-9 - PubMed
  26. Adv Drug Deliv Rev. 2012 Sep;64(12):1063-77 - PubMed
  27. Arch Orthop Trauma Surg. 2011 Nov;131(11):1591-600 - PubMed
  28. J Bone Joint Surg Am. 2003;85-A Suppl 1:S18-20 - PubMed
  29. J Arthroplasty. 1996 Apr;11(3):235-41 - PubMed
  30. J Arthroplasty. 2012 Jun;27(6):1069-74 - PubMed
  31. Clin Orthop Relat Res. 2009 Jan;467(1):194-8 - PubMed

Publication Types