Display options
Share it on

Int J Nephrol. 2014;2014:718147. doi: 10.1155/2014/718147. Epub 2014 May 20.

A new method to make 24-hour urine collection more convenient: a validity study.

International journal of nephrology

Pooneh Nabavizadeh, Shadi Ghadermarzi, Mohammad Fakhri

Affiliations

  1. School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.

PMID: 24963405 PMCID: PMC4055097 DOI: 10.1155/2014/718147

Abstract

Background and Objectives. This study proposes a novel urine collection device that can divide each urine collection into 20 parts and store and cool just one part. The aim of the current study is to compare measured biomarkers from the proposed urine collection device to those of conventional 24-hour sampling method. We also hypothesized that the new method would significantly increase patients' adherence to the timed urine collection. Methods. Two 24-hour urine samples with the conventional method and with the new automated urine collection device that uses just one-twentieth of each void were obtained from 40 healthy volunteers. Urine parameters including volume, creatinine, and protein levels were compared between the two methods and the agreement of two measurements for each subject was reported through Bland-Altman plots. Results. Our results confirmed that for all three variables, there is a positive correlation (P < 0.001) between the two measurements and high degree of agreement could be seen in Bland-Altman plots. Moreover, more subjects reported the new method as "more convenient" for 24-hour urine collection. Conclusions. Our results clearly indicate that a fixed proportion of each void may significantly reduce the urine volume in timed collections and this, in turn, may increase subjects' adherence to this difficult sampling.

References

  1. Lancet. 1986 Feb 8;1(8476):307-10 - PubMed
  2. Lancet. 1995 Oct 21;346(8982):1085-7 - PubMed
  3. Clin Nephrol. 1997 Apr;47(4):222-8 - PubMed
  4. Clin Nephrol. 2004 Aug;62(2):97-103 - PubMed
  5. Ann Intern Med. 1995 Nov 15;123(10):754-62 - PubMed
  6. J Am Soc Nephrol. 2003 Oct;14(10):2573-80 - PubMed
  7. Ann Clin Biochem. 2005 Sep;42(Pt 5):321-45 - PubMed
  8. Kidney Int. 2002 May;61(5):1567-76 - PubMed
  9. Biochem Med (Zagreb). 2013;23(3):316-20 - PubMed
  10. S Afr Med J. 2007 Oct;97(10):968-70 - PubMed
  11. Nephrol Dial Transplant. 2002 Nov;17(11):1909-13 - PubMed
  12. Arch Intern Med. 2005 Apr 25;165(8):947-53 - PubMed

Publication Types