Display options
Share it on

J Surg Case Rep. 2013 Feb 07;2013(2). doi: 10.1093/jscr/rjs047.

A case of metaplastic breast cancer in a man.

Journal of surgical case reports

James Geoffrey Barr, Elizabeth Sarah Jane Clayton, Wendy Sotheran

Affiliations

  1. Breast Surgery Department, St Richard's Hospital, Chichester, UK [email protected].
  2. Breast Surgery Department, St Richard's Hospital, Chichester, UK.

PMID: 24964410 PMCID: PMC3789653 DOI: 10.1093/jscr/rjs047

Abstract

Metaplastic breast cancers (MPBCs) represent <1% of breast cancers. Reports of MPBC in men are limited to case reports. We report a case of MPBC with pulmonary metastasis occurring in a 59-year-old man who initially presented with a presumed breast abscess. Histology from the breast lesion revealed a poorly differentiated carcinoma and a computed tomography scan showed an ulcerative right-sided breast mass and an area of scarring in the apex of the left lung. The breast lesion and the lung lesion were resected separately and the histology from the lung showed a poorly differentiated carcinoma with sarcomatous features in keeping with metastasis from a primary breast cancer. Our patient then proceeded to chemotherapy with FEC 100 regimen (5-fluorouracil, epirubicin and cyclophosphamide). MPBC is an aggressive breast cancer that has a propensity to metastasis to the lungs. Prognosis is poor.

Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2013.

References

  1. Arch Pathol Lab Med. 2012 Aug;136(8):896-900 - PubMed
  2. Ann Oncol. 1999 Apr;10(4):413-9 - PubMed
  3. Ann Surg Oncol. 2007 Jan;14(1):166-73 - PubMed
  4. Int J Surg Pathol. 2012 Jun;20(3):284-96 - PubMed
  5. Anticancer Res. 2000 May-Jun;20(3B):2219-22 - PubMed
  6. ISRN Oncol. 2012;2012:706162 - PubMed
  7. Acta Oncol. 2006;45(2):188-95 - PubMed

Publication Types