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J Diabetes Investig. 2013 Jan 29;4(1):94-6. doi: 10.1111/j.2040-1124.2012.00239.x. Epub 2012 Aug 30.

Successful control of a case of severe insulin allergy with liraglutide.

Journal of diabetes investigation

Daiji Kawanami, Tomoko Ito, Yui Watanabe, Jun Kinoshita, Masaya Sakamoto, Tsuyoshi Isaka, Kazunori Utsunomiya

Affiliations

  1. Division of Diabetes, Metabolism and Endocrinology Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.

PMID: 24843637 PMCID: PMC4019294 DOI: 10.1111/j.2040-1124.2012.00239.x

Abstract

A 72-year-old woman presented with repeated hypoglycemic and hyperglycemic episodes because of an insulin allergy. On admission, she was diagnosed with type B insulin resistance syndrome. She was also found to have anti-insulin antibodies. After steroid therapy, glycemic control improved dramatically accompanied by the disappearance of the insulin allergy. We then introduced liraglutide, which successfully stabilized her glycemic episodes without allergic reactions. Liraglutide might be useful to treat patients with severe insulin allergy.

Keywords: Insulin allergy; Liraglutide; Type B insulin resistance syndrome

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