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Asia Pac J Clin Oncol. 2016 Jun;12(2):e347-e349. doi: 10.1111/ajco.12204. Epub 2014 Jun 17.

First reported case of interferon-alpha-induced sarcoidosis in an Asian patient with malignant melanoma.

Asia-Pacific journal of clinical oncology

Eun Kyoung Jeon, Jihyoung Hong, Sook Hee Hong, Ji Young Kang, Gyeongsin Park, Myeong Im Ahn, Jun Young Lee, Jinhyoung Kang

Affiliations

  1. Division of Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  2. Division of Pulmonology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  3. Department of Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  4. Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  5. Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

PMID: 24935527 DOI: 10.1111/ajco.12204

Abstract

Anticancer agents can induce sarcoidosis. Interferon-alpha, which is used for the treatment of malignant melanoma and renal cell cancer, is one causative agent of sarcoidosis. However, there are few reports of interferon-alpha-induced sarcoidosis in patients with malignant melanoma. Clinically, it is important to consider the possibility of sarcoidosis in such patients because it could be easily regarded as a metastatic lesion due to underlying malignancy and given unnecessary treatment. Here, we report on the first case of interferon-alpha-induced sarcoidosis in an Asian melanoma patient.

© 2014 Wiley Publishing Asia Pty Ltd.

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