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Khatri PM, Bacha S. Systemic antimicrobial therapy (minocycline) as an adjunct to non-surgical approach to recurrent chronic generalized gingival hyperplasia. J Indian Soc Periodontol. 2014;18(2):249-53doi: 10.4103/0972-124X.131345.
Khatri, P. M., & Bacha, S. (2014). Systemic antimicrobial therapy (minocycline) as an adjunct to non-surgical approach to recurrent chronic generalized gingival hyperplasia. Journal of Indian Society of Periodontology, 18(2), 249-53. https://doi.org/10.4103/0972-124X.131345
Khatri, Parag M, and Bacha, Shraddanand. "Systemic antimicrobial therapy (minocycline) as an adjunct to non-surgical approach to recurrent chronic generalized gingival hyperplasia." Journal of Indian Society of Periodontology vol. 18,2 (2014): 249-53. doi: https://doi.org/10.4103/0972-124X.131345
Khatri PM, Bacha S. Systemic antimicrobial therapy (minocycline) as an adjunct to non-surgical approach to recurrent chronic generalized gingival hyperplasia. J Indian Soc Periodontol. 2014 Mar;18(2):249-53. doi: 10.4103/0972-124X.131345. PMID: 24872639; PMCID: PMC4033897.
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J Indian Soc Periodontol. 2014 Mar;18(2):249-53. doi: 10.4103/0972-124X.131345.

Systemic antimicrobial therapy (minocycline) as an adjunct to non-surgical approach to recurrent chronic generalized gingival hyperplasia.

Journal of Indian Society of Periodontology

Parag M Khatri, Shraddanand Bacha

Affiliations

  1. Department of Periodontics, College of Dental Science, Amargadh, Bhavnagar, Gujarat, India.

PMID: 24872639 PMCID: PMC4033897 DOI: 10.4103/0972-124X.131345

Abstract

Systemic antibiotic treatment has emerged as a powerful adjunct to conventional mechanical debridement for therapeutic management of the periodontal diseases. The conceptual basis for treating periodontal diseases as infections is particularly attractive in part because of substantial data indicating that these diseases may be associated with specific putative pathogens. Further, discrete groups of patients respond well to systemic antibiotics and exhibit improvement of clinical parameters, including attachment level and inflammation. This bacterial-host interaction, which is ever-so-present in periodontitis, directs us toward utilizing antimicrobial agents along with the routine mechanical debridement. This case report presents a case of a female patient with recurrence of the chronic generalized periodontitis with gingival enlargement, which is treated thrice by referral dentist. A through clinical examination was carried out pre-operatively and treatment was planned with systemic minocycline in conjunction with the conventional non-surgical approach. There was a significant reduction of pocket depth, gain in attachment with dramatic improvement clinically.

Keywords: Gingival enlargement; minocycline; refractory periodontitis; systemic drug therapy

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