Display options
Share it on

Rep Pract Oncol Radiother. 2013 Aug 13;19(2):114-9. doi: 10.1016/j.rpor.2013.07.006. eCollection 2014 Mar.

First treatment of mycosis fungoides by total skin electron beam (TSEB) therapy in Greece.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Stefanos Diamantopoulos, Kalliopi Platoni, Vassilis Kouloulias, Panayiotis Pantelakos, Maria Dilvoi, Evangelia Papadavid, Christina Antoniou, Efstathios Efstathopoulos

Affiliations

  1. Radiation Therapy Unit, University General Hospital 'Attikon', Athens, Greece.
  2. Dermatology Department, University General Hospital 'Attikon', Athens, Greece.
  3. Dermatology Department, Andreas Syggros Hospital, Athens, Greece.

PMID: 24936330 PMCID: PMC4054992 DOI: 10.1016/j.rpor.2013.07.006

Abstract

BACKGROUND: Mycosis fungoides (MF), the most common subtype of cutaneous T-Cell Lymphoma (CTCL), is a rare chronic skin neoplasia. Total skin electron irradiation has been employed along with a variety of other topical or systemic treatments for MF management.

AIM: To report the first case treated by TSEB irradiation protocol in Greece.

MATERIALS AND METHODS: A fractionated 36 Gy total skin electron beam (TSEB) therapy was prescribed to a 65-years-old male patient with mycosis fungoides (MF), stage IIB, refractory to several treatments during a 20-year period. Dose uniform delivery was monitored by thermo-luminescence dosimetry.

RESULTS AND DISCUSSION: The homogeneous skin dose distribution resulted in a complete clinical response. Limited, irradiation-oriented, side effects appeared.

CONCLUSIONS: The first TSEB irradiation prescription in Greek medical chronicles was proved effective in this case of tumor stage MF (T3-IIB), which had been refractory to several single or combination treatments.

Keywords: Mycosis fungoides; Radiation therapy; TSEB

References

  1. Br J Dermatol. 2012 Feb;166(2):399-404 - PubMed
  2. Hematol Oncol Clin North Am. 2003 Dec;17(6):1421-34 - PubMed
  3. Phys Med. 2012 Apr;28(2):174-82 - PubMed
  4. Blood. 2007 Sep 15;110(6):1713-22 - PubMed
  5. Phys Med. 2011 Apr;27(2):62-8 - PubMed
  6. J ICRU. 2004 Jun;4(1):2 - PubMed
  7. Cancer Control. 2007 Apr;14(2):102-11 - PubMed
  8. Arch Dermatol. 2002 Jan;138(1):42-8 - PubMed
  9. J Cutan Med Surg. 2010 Jan-Feb;14(1):1-6 - PubMed
  10. Cancer. 1996 May 1;77(9):1912-7 - PubMed

Publication Types