Diabetes Res Clin Pract. 2014 Aug;105(2):151-63. doi: 10.1016/j.diabres.2014.03.020. Epub 2014 Apr 18.
Cost-of-illness studies of diabetes mellitus: a systematic review.
Diabetes research and clinical practice
Charmaine S Ng, Joyce Y C Lee, Matthias Phs Toh, Yu Ko
Affiliations
Affiliations
- Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore.
- Information Management, Corporate Development, National Healthcare Group, Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
- Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, Singapore. Electronic address: [email protected].
PMID: 24814877
DOI: 10.1016/j.diabres.2014.03.020
Abstract
BACKGROUND: Diabetes mellitus (DM) is recognised as a major health problem.
OBJECTIVES: The aims of this study are two-fold: (1) to describe the methods used in the identified cost-of-illness (COI) studies of DM and (2) to summarise their study findings regarding the economic impact of DM.
METHODS: This is a systematic review of MEDLINE and Scopus journal articles reporting the cost of type 1 and/or 2 DM that were published in English from 2007 to 2011. Costs reported in the included studies were converted to US dollars.
RESULTS: The systematic search yielded 30 articles. The studies varied considerably in their study design, perspective and included cost categories. Estimates for the total annual costs of DM ranged from US$141.6 million to US$174 billion; direct costs ranged from US$150 to US$14,060 per patient per year (pppy) whereas indirect costs ranged from US$39.6 to US$7,164 pppy. Inpatient cost was the major contributor to direct cost in half of the studies that included inpatient costs, physician services and medications.
CONCLUSION: There is a considerable economic burden associated with DM. Future research should focus on improving methods of estimating costs, enhancing the interpretation of study findings and facilitating comparisons between studies.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Keywords: Cost analysis; Cost of disease; Cost-of-illness; Diabetes; Economic burden; Healthcare costs
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