Display options
Share it on

J Int Oral Health. 2014 Apr;6(2):126-8. Epub 2014 Apr 26.

Assessment of oral side effects of Antiepileptic drugs and traumatic oro-facial injuries encountered in Epileptic children.

Journal of international oral health : JIOH

P A Fazal Ghafoor, Mohammed Rafeeq, Alok Dubey

Affiliations

  1. Department of Neurology, MES Medical College, Perinthalmanna, Kerala,, India.
  2. Department of Neurology, MES MedicaI College, Perinthalmanna, Kerala, India.
  3. Department of Pedodontics & Preventive Dentistry, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, lndia.

PMID: 24876713 PMCID: PMC4037794

Abstract

BACKGROUND: Epilepsy is a chronic disorder with unpredictably recurring seizure. Uncontrolled attacks can put patients at risk of suffering oro-facial trauma. Antiepileptic drugs (AED) provide satisfactory control of seizures in most of the patients with epilepsy. However use of AED has been found to cause many side effects inclusive of side effects in the oral cavity also.

MATERIALS & METHODS: This study was conducted on 150 epileptic children, who were on anti epileptic medication for one year.

RESULTS: Gingival over growth was seen as common side effect of the AED drugs. Lip and cheek biting were the most common soft tissue injury, while tooth fracture was the most common hard tissue dental injury.

CONCLUSION: General physicians, physicians & dentists should be well aware of the potential side effects of AED. A Dentist should be well versed and trained to manage oro-facial injuries in the emergency department. How to cite the article: Ghafoor PA, Rafeeq M, Dubey A. Assessment of oral side effects of Antiepileptic drugs and traumaticoro-facial injuries encountered in Epileptic children. J Int Oral Health 2014;6(2):126-8.

Keywords: AED; epilepsy; gingival hyperplasia; nocturnal tongue biting; phenytoin; seizure

References

  1. Contemp Clin Dent. 2014 Jan;5(1):59-66 - PubMed
  2. Indian J Psychol Med. 2010 Jan;32(1):59-60 - PubMed
  3. Seizure. 2014 Mar;23(3):184-90 - PubMed
  4. Epilepsy Behav. 2014 Mar;32:49-54 - PubMed
  5. J Contemp Dent Pract. 2008 Jan 01;9(1):54-62 - PubMed
  6. J Can Dent Assoc. 2007 Feb;73(1):71-6 - PubMed
  7. J Oral Maxillofac Surg. 2005 Jul;63(7):996-1005 - PubMed
  8. P T. 2010 Jul;35(7):392-415 - PubMed
  9. Arq Neuropsiquiatr. 2011 Jun;69(3):491-5 - PubMed
  10. Seizure. 2013 May;22(4):328 - PubMed
  11. J Med Assoc Thai. 1997 Aug;80(8):500-7 - PubMed

Publication Types